@article{c5c07b7d9a7c470897d60d7813cb407b,
title = "Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia",
abstract = "A pooled analysis of 1238 patients with chronic lymphocytic leukemia/small lymphocytic lymphoma from three phase 3 studies found that genomic risk factors were not associated with shorter progression-free survival (PFS) or overall survival for patients treated with ibrutinib. Ibrutinib-treated patients with del(11q) were found to have a longer PFS than those without del(11q). These results suggest less prognostic relevance for certain genomic risk factors with ibrutinib treatment.",
keywords = "Prognostic factors, Risk factors, Small lymphocytic lymphoma, Survival",
author = "Kipps, {Thomas J.} and Graeme Fraser and Coutre, {Steven E.} and Brown, {Jennifer R.} and Barrientos, {Jacqueline C.} and Barr, {Paul M.} and Byrd, {John C.} and O'Brien, {Susan M.} and Dilhuydy, {Marie Sarah} and Peter Hillmen and Ulrich Jaeger and Carol Moreno and Paula Cramer and Stephan Stilgenbauer and Chanan-Khan, {Asher A.} and Michelle Mahler and Mariya Salman and Karl Eckert and Solman, {Isabelle G.} and Sriram Balasubramanian and Mei Cheng and Anil Londhe and Joi Ninomoto and Angela Howes and James, {Danelle F.} and Michael Hallek",
note = "Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = nov,
doi = "10.1016/j.clml.2019.07.004",
language = "English (US)",
volume = "19",
pages = "715--722.e6",
journal = "Clinical Lymphoma, Myeloma and Leukemia",
issn = "2152-2650",
publisher = "Cancer Media Group",
number = "11",
}