Long-term prognosis of inducible ventricular flutter: Not an innocent finding

Osnat Gurevitz, Sami Viskin, Michael Glikson, Karla V. Ballman, A. Gabriela Rosales, Win Kuang Shen, Stephen C. Hammill, Paul A. Friedman

Research output: Contribution to journalArticle

16 Scopus citations


Background The prognostic significance of ventricular flutter (VFL) induced during programmed electrical stimulation (PES) is currently unknown. Methods This study examined patients who had PES-induced VFL and assessed their long-term prognosis compared with patients who had inducible sustained monomorphic ventricular tachycardia (SMVT). Results Of 3414 patients undergoing PES, 74 (2%) had sustained VFL. They were compared with a group of 71 patients undergoing PES in the same time frame who had inducible SMVT. Patients with inducible VFL had a higher ejection fraction than patients with SMVT (0.39 vs 0.33; P = .05). More aggressive pacing was required for arrhythmia induction in patients with VFL, with more stimuli (2.7 ± 0.5 vs 2.2 ± 0.6; P <.01) and tighter S2, S3, and S4 intervals. After a mean follow-up of 30 ± 31 months, the mortality rate was 34% in patients with VFL and 30% in patients with SMVT (P = .41). No difference in the 2 groups in overall survival or a combined end point of sudden death or appropriate implantable cardioverter defibrillator shock was revealed with Kaplan-Meier analysis. Conclusion The long-term prognosis of patients with inducible VFL is similar to that of patients with inducible SMVT, even when VFL is induced with a relatively aggressive protocol.

Original languageEnglish (US)
Pages (from-to)649-654
Number of pages6
JournalAmerican Heart Journal
Issue number4
StatePublished - Apr 1 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Gurevitz, O., Viskin, S., Glikson, M., Ballman, K. V., Rosales, A. G., Shen, W. K., Hammill, S. C., & Friedman, P. A. (2004). Long-term prognosis of inducible ventricular flutter: Not an innocent finding. American Heart Journal, 147(4), 649-654. https://doi.org/10.1016/j.ahj.2003.11.012