Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy

Brian D. Moseley, Shobhit Sinha, Fredric B. Meyer, W. Richard Marsh, Jeffrey W. Britton

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p= 0.021), the absence of generalized IEDs on postoperative EEG (p= 0.024), and the presence of focal slowing on postoperative EEG (p= 0.045).

Original languageEnglish (US)
Pages (from-to)171-175
Number of pages5
JournalEpilepsy Research
Volume99
Issue number1-2
DOIs
StatePublished - Mar 1 2012

Keywords

  • Bilateral synchrony
  • Generalized EEG
  • Surgical outcome
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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