Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy

Brian D. Moseley; Shobhit Sinha; Fredric B. Meyer; W. Richard Marsh; Jeffrey W. Britton

doi:10.1016/j.eplepsyres.2011.10.007

Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy

Brian D. Moseley, Shobhit Sinha, Fredric B. Meyer, W. Richard Marsh, Jeffrey W. Britton

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p= 0.021), the absence of generalized IEDs on postoperative EEG (p= 0.024), and the presence of focal slowing on postoperative EEG (p= 0.045).

Original language	English (US)
Pages (from-to)	171-175
Number of pages	5
Journal	Epilepsy Research
Volume	99
Issue number	1-2
DOIs	https://doi.org/10.1016/j.eplepsyres.2011.10.007
State	Published - Mar 2012

Keywords

Bilateral synchrony
Generalized EEG
Surgical outcome
Temporal lobe epilepsy

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/j.eplepsyres.2011.10.007

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title = "Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy",

abstract = "We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p= 0.021), the absence of generalized IEDs on postoperative EEG (p= 0.024), and the presence of focal slowing on postoperative EEG (p= 0.045).",

keywords = "Bilateral synchrony, Generalized EEG, Surgical outcome, Temporal lobe epilepsy",

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AU - Marsh, W. Richard

AU - Britton, Jeffrey W.

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AB - We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p= 0.021), the absence of generalized IEDs on postoperative EEG (p= 0.024), and the presence of focal slowing on postoperative EEG (p= 0.045).

KW - Bilateral synchrony

KW - Generalized EEG

KW - Surgical outcome

KW - Temporal lobe epilepsy

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Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy

Abstract

Keywords

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