Long-Term outcome of symptomatic infantile spasms established by video-electroencephalography (EEG) monitoring

Maria A. Montenegro, Karen Eck, Susan Jacob, Joshua Cappell, Claudia Chriboga, Ronald Emerson, Marc C. Patterson, Cigdem I. Akman

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In this study, we examine the long-term clinical outcome of children with symptomatic infantile spasm. The children between 2 and 18 years of age diagnosed with symptomatic infantile spasms were reviewed. Sixty-eight children (age range, 2-13 years; mean, 4.5 years) met the inclusion criteria. Children who underwent epilepsy surgery were excluded. Age of onset for infantile spasms ranged from 1 to 24 months (mean, 7.1 months). Developmental delay was noted in all; there was seizure freedom in 14 children (20.5%). Infantile spasms were reported as the only seizure type in 10 (14.5%) children older than age 2 years. During the follow-up; symptomatic generalized epilepsy was diagnosed in 23 childern (34%) and focal epilepsy in 21 (31%). The long-term outcome of these children remains unchanged in the majority of the children with symptomatic infantile spasms. We could not establish any risk factor that might be related to favorable or adverse outcome.

Original languageEnglish (US)
Pages (from-to)1288-1292
Number of pages5
JournalJournal of Child Neurology
Volume23
Issue number11
DOIs
StatePublished - 2008
Externally publishedYes

Fingerprint

Infantile Spasms
Electroencephalography
Seizures
Generalized Epilepsy
Partial Epilepsy
Age of Onset
Epilepsy

Keywords

  • Epilepsy
  • Symptomatic infantile spasms
  • Video-electroencephalography (EEG) monitoring

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Montenegro, M. A., Eck, K., Jacob, S., Cappell, J., Chriboga, C., Emerson, R., ... Akman, C. I. (2008). Long-Term outcome of symptomatic infantile spasms established by video-electroencephalography (EEG) monitoring. Journal of Child Neurology, 23(11), 1288-1292. https://doi.org/10.1177/0883073808318540

Long-Term outcome of symptomatic infantile spasms established by video-electroencephalography (EEG) monitoring. / Montenegro, Maria A.; Eck, Karen; Jacob, Susan; Cappell, Joshua; Chriboga, Claudia; Emerson, Ronald; Patterson, Marc C.; Akman, Cigdem I.

In: Journal of Child Neurology, Vol. 23, No. 11, 2008, p. 1288-1292.

Research output: Contribution to journalArticle

Montenegro, MA, Eck, K, Jacob, S, Cappell, J, Chriboga, C, Emerson, R, Patterson, MC & Akman, CI 2008, 'Long-Term outcome of symptomatic infantile spasms established by video-electroencephalography (EEG) monitoring', Journal of Child Neurology, vol. 23, no. 11, pp. 1288-1292. https://doi.org/10.1177/0883073808318540
Montenegro, Maria A. ; Eck, Karen ; Jacob, Susan ; Cappell, Joshua ; Chriboga, Claudia ; Emerson, Ronald ; Patterson, Marc C. ; Akman, Cigdem I. / Long-Term outcome of symptomatic infantile spasms established by video-electroencephalography (EEG) monitoring. In: Journal of Child Neurology. 2008 ; Vol. 23, No. 11. pp. 1288-1292.
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