Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma

Eric J. Moore, Steven M. Olsen, Rebecca R. Laborde, Joaquín J. García, Francis J. Walsh, Daniel L. Price, Jeffrey R. Janus, Jan Kasperbauer, Kerry D. Olsen

Research output: Contribution to journalArticle

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Abstract

Objective: To examine the long-term functional and oncologic results in patients who underwent transoral robotic surgery (TORS) as primary therapy or as part of combined therapy for oropharyngeal squamous cell carcinoma arising in the tonsil or base of tongue. Patients and Methods: We reviewed a prospective TORS database of patients with squamous cell carcinoma arising in the tonsil or base of tongue treated between March 2007 and February 2009 to determine oncologic outcomes at 24 months or more of follow-up. The presenting tumor stage, histopathologic factors, surgical margins, and adjuvant treatment extent were evaluated. Functional outcomes included gastrostomy tube dependence and tracheostomy dependence. Oncologic outcomes included local, regional, and distant control and disease-specific and recurrence-free survival. Results: A total of 66 TORS patients were followed up for a minimum of 2 years. Most (97.0%; 64 of 66) were able to eat orally within 3 weeks after surgery before starting adjuvant therapy. Long-term gastrostomy tube use was required in 3 of the 66 (4.5%) and long-term tracheotomy in 1 (1.5%). Three-year estimated local control and regional control were 97.0% and 94.0%, respectively. Two-year disease-specific survival and recurrence-free survival were 95.1% and 92.4%, respectively. Conclusion: With appropriate adjuvant therapy, TORS achieves excellent functional results for patients with oropharyngeal squamous cell carcinoma. Oncologic outcomes are equivalent or superior to results of other surgical and nonsurgical treatments.

Original languageEnglish (US)
Pages (from-to)219-225
Number of pages7
JournalMayo Clinic Proceedings
Volume87
Issue number3
DOIs
StatePublished - Jan 1 2012

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Robotics
Squamous Cell Carcinoma
Gastrostomy
Palatine Tonsil
Tongue
Survival
Therapeutics
Recurrence
Tracheotomy
Tracheostomy
Databases
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Moore, E. J., Olsen, S. M., Laborde, R. R., García, J. J., Walsh, F. J., Price, D. L., ... Olsen, K. D. (2012). Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma. Mayo Clinic Proceedings, 87(3), 219-225. https://doi.org/10.1016/j.mayocp.2011.10.007

Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma. / Moore, Eric J.; Olsen, Steven M.; Laborde, Rebecca R.; García, Joaquín J.; Walsh, Francis J.; Price, Daniel L.; Janus, Jeffrey R.; Kasperbauer, Jan; Olsen, Kerry D.

In: Mayo Clinic Proceedings, Vol. 87, No. 3, 01.01.2012, p. 219-225.

Research output: Contribution to journalArticle

Moore, EJ, Olsen, SM, Laborde, RR, García, JJ, Walsh, FJ, Price, DL, Janus, JR, Kasperbauer, J & Olsen, KD 2012, 'Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma', Mayo Clinic Proceedings, vol. 87, no. 3, pp. 219-225. https://doi.org/10.1016/j.mayocp.2011.10.007
Moore, Eric J. ; Olsen, Steven M. ; Laborde, Rebecca R. ; García, Joaquín J. ; Walsh, Francis J. ; Price, Daniel L. ; Janus, Jeffrey R. ; Kasperbauer, Jan ; Olsen, Kerry D. / Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma. In: Mayo Clinic Proceedings. 2012 ; Vol. 87, No. 3. pp. 219-225.
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AU - Walsh, Francis J.

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