TY - JOUR
T1 - Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains.
AU - Yang, Marjorie U.
AU - Yaroslavsky, Anna N.
AU - Farinelli, William A.
AU - Flotte, Thomas J.
AU - Rius-Diaz, Francisca
AU - Tsao, Sandy S.
AU - Anderson, R. Rox
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2005/3
Y1 - 2005/3
N2 - OBJECTIVE: Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength. METHODS: PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs. RESULTS: MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm 2 . Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery. CONCLUSION: Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring.
AB - OBJECTIVE: Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength. METHODS: PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs. RESULTS: MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm 2 . Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery. CONCLUSION: Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring.
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U2 - 10.1016/j.jaad.2004.10.876
DO - 10.1016/j.jaad.2004.10.876
M3 - Article
C2 - 15761427
AN - SCOPUS:24944530031
SN - 0190-9622
VL - 52
SP - 480
EP - 490
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 3 Pt 1
ER -