Localized scleroderma (morphea) and antibody to Borrelia burgdorferi

J. M. Hoesly, L. E. Mertz, R. K. Winkelmann

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55 Citations (Scopus)

Abstract

Enzyme-linked immunosorbent assay (ELISA) and immunofluorescence assay (IFA) were performed in 25 and 32 cases of morphea, respectively. The more sensitive and specific ELISA was positive in only 1 of 25 cases and the mean value was lower in cases of morphea than in controls. IFA showed minimally reactive titers in 6 (19%) of 32 cases. There were an additional six cases with borderline titers. These data indicate that there is no specific association between Borrelia burgdorferi infection and morphea but that patients with morphea tend to have circulating antibodies that are cross-reactive.

Original languageEnglish (US)
Pages (from-to)455-458
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume17
Issue number3
StatePublished - 1987

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Localized Scleroderma
Borrelia burgdorferi
Antibodies
Fluorescent Antibody Technique
Enzyme-Linked Immunosorbent Assay
Borrelia Infections

ASJC Scopus subject areas

  • Dermatology

Cite this

Hoesly, J. M., Mertz, L. E., & Winkelmann, R. K. (1987). Localized scleroderma (morphea) and antibody to Borrelia burgdorferi. Journal of the American Academy of Dermatology, 17(3), 455-458.

Localized scleroderma (morphea) and antibody to Borrelia burgdorferi. / Hoesly, J. M.; Mertz, L. E.; Winkelmann, R. K.

In: Journal of the American Academy of Dermatology, Vol. 17, No. 3, 1987, p. 455-458.

Research output: Contribution to journalArticle

Hoesly, JM, Mertz, LE & Winkelmann, RK 1987, 'Localized scleroderma (morphea) and antibody to Borrelia burgdorferi', Journal of the American Academy of Dermatology, vol. 17, no. 3, pp. 455-458.
Hoesly, J. M. ; Mertz, L. E. ; Winkelmann, R. K. / Localized scleroderma (morphea) and antibody to Borrelia burgdorferi. In: Journal of the American Academy of Dermatology. 1987 ; Vol. 17, No. 3. pp. 455-458.
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