Living donor liver transplantation in polycystic liver disease

Kristin L. Mekeel; Adyr A. Moss; Kunam S. Reddy; David D. Douglas; Hugo E. Vargas; Elizabeth J. Carey; Thomas J. Byrne; M. E. Harrison; Jorge Rakela; David C. Mulligan

doi:10.1002/lt.21423

Living donor liver transplantation in polycystic liver disease

Kristin L. Mekeel, Adyr A. Moss, Kunam S. Reddy, David D. Douglas, Hugo E. Vargas, Elizabeth J. Carey, Thomas J. Byrne, M. E. Harrison, Jorge Rakela, David C. Mulligan

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

In the current Model for End-Stage Liver Disease system, patients with polycystic liver disease (PCLD) who have a poor quality of life secondary to their massive hepatomegaly are no longer competitive for a deceased donor liver transplant if their liver function is well preserved. Traditionally, a caval resection has been advocated in these patients because of the difficulty of the hepatectomy with hepatomegaly, which makes living donation impossible. This series looks at 3 patients who underwent a caval sparing hepatectomy and subsequent living donor liver transplantation (LDLT) for PCLD. Graft and patient survival was 100%, and there were few complications in either donors or recipients. LDLT is an ideal option for patients with PCLD and preserved liver function but poor quality of life.

Original language	English (US)
Pages (from-to)	680-683
Number of pages	4
Journal	Liver Transplantation
Volume	14
Issue number	5
DOIs	https://doi.org/10.1002/lt.21423
State	Published - May 2008

ASJC Scopus subject areas

Surgery
Hepatology
Transplantation

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10.1002/lt.21423

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title = "Living donor liver transplantation in polycystic liver disease",

abstract = "In the current Model for End-Stage Liver Disease system, patients with polycystic liver disease (PCLD) who have a poor quality of life secondary to their massive hepatomegaly are no longer competitive for a deceased donor liver transplant if their liver function is well preserved. Traditionally, a caval resection has been advocated in these patients because of the difficulty of the hepatectomy with hepatomegaly, which makes living donation impossible. This series looks at 3 patients who underwent a caval sparing hepatectomy and subsequent living donor liver transplantation (LDLT) for PCLD. Graft and patient survival was 100%, and there were few complications in either donors or recipients. LDLT is an ideal option for patients with PCLD and preserved liver function but poor quality of life.",

author = "Mekeel, {Kristin L.} and Moss, {Adyr A.} and Reddy, {Kunam S.} and Douglas, {David D.} and Vargas, {Hugo E.} and Carey, {Elizabeth J.} and Byrne, {Thomas J.} and Harrison, {M. E.} and Jorge Rakela and Mulligan, {David C.}",

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AU - Mekeel, Kristin L.

AU - Moss, Adyr A.

AU - Reddy, Kunam S.

AU - Douglas, David D.

AU - Vargas, Hugo E.

AU - Carey, Elizabeth J.

AU - Byrne, Thomas J.

AU - Harrison, M. E.

AU - Rakela, Jorge

AU - Mulligan, David C.

PY - 2008/5

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AB - In the current Model for End-Stage Liver Disease system, patients with polycystic liver disease (PCLD) who have a poor quality of life secondary to their massive hepatomegaly are no longer competitive for a deceased donor liver transplant if their liver function is well preserved. Traditionally, a caval resection has been advocated in these patients because of the difficulty of the hepatectomy with hepatomegaly, which makes living donation impossible. This series looks at 3 patients who underwent a caval sparing hepatectomy and subsequent living donor liver transplantation (LDLT) for PCLD. Graft and patient survival was 100%, and there were few complications in either donors or recipients. LDLT is an ideal option for patients with PCLD and preserved liver function but poor quality of life.

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Living donor liver transplantation in polycystic liver disease

Abstract

ASJC Scopus subject areas

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