Liver transplantation for congenital biliary dilatation

A single-center experience

Tomohide Hori, Fumitaka Oike, Yasuhiro Ogura, Kohei Ogawa, Koichiro Hata, Yukihide Yonekawa, Mikiko Ueda, Seisuke Sakamoto, Mureo Kasahara, Hiroto Egawa, Yasutsugu Takada, Toshimi Kaido, Etsuro Hatano, Justin H Nguyen, Feng Chen, Ann Marie T Baine, Shinji Uemoto

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Congenital biliary dilatation is a rare disease. Although the possibility of refractory cholangitis and/or the frequency of malignant tumors legitimize hepatobiliary surgery, repeated cholangitis and biliary obstruction result in secondary liver cirrhosis even after polysurgery. There are no definitive guidelines on liver transplantation for congenital biliary dilatation. Patients: A total of 1,101 liver transplantation recipients were enrolled in this study. Eleven patients with congenital biliary dilatation including 5 patients with Caroli's disease were retrospectively analyzed in detail. Results: Nine of 11 patients underwent initial operations before liver transplantation while 2 patients with Caroli's disease received liver transplantation as initial surgery, with good outcomes. All patients had intractable symptoms caused by liver cirrhosis, and growth delay was considerable in patients aged

Original languageEnglish (US)
Pages (from-to)492-501
Number of pages10
JournalDigestive Surgery
Volume27
Issue number6
DOIs
StatePublished - Jan 2011

Fingerprint

Liver Transplantation
Dilatation
Caroli Disease
Cholangitis
Liver Cirrhosis
Rare Diseases
Guidelines
Growth
Neoplasms

Keywords

  • Caroli's disease
  • Congenital biliary dilatation
  • Liver transplantation

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Hori, T., Oike, F., Ogura, Y., Ogawa, K., Hata, K., Yonekawa, Y., ... Uemoto, S. (2011). Liver transplantation for congenital biliary dilatation: A single-center experience. Digestive Surgery, 27(6), 492-501. https://doi.org/10.1159/000319373

Liver transplantation for congenital biliary dilatation : A single-center experience. / Hori, Tomohide; Oike, Fumitaka; Ogura, Yasuhiro; Ogawa, Kohei; Hata, Koichiro; Yonekawa, Yukihide; Ueda, Mikiko; Sakamoto, Seisuke; Kasahara, Mureo; Egawa, Hiroto; Takada, Yasutsugu; Kaido, Toshimi; Hatano, Etsuro; Nguyen, Justin H; Chen, Feng; Baine, Ann Marie T; Uemoto, Shinji.

In: Digestive Surgery, Vol. 27, No. 6, 01.2011, p. 492-501.

Research output: Contribution to journalArticle

Hori, T, Oike, F, Ogura, Y, Ogawa, K, Hata, K, Yonekawa, Y, Ueda, M, Sakamoto, S, Kasahara, M, Egawa, H, Takada, Y, Kaido, T, Hatano, E, Nguyen, JH, Chen, F, Baine, AMT & Uemoto, S 2011, 'Liver transplantation for congenital biliary dilatation: A single-center experience', Digestive Surgery, vol. 27, no. 6, pp. 492-501. https://doi.org/10.1159/000319373
Hori, Tomohide ; Oike, Fumitaka ; Ogura, Yasuhiro ; Ogawa, Kohei ; Hata, Koichiro ; Yonekawa, Yukihide ; Ueda, Mikiko ; Sakamoto, Seisuke ; Kasahara, Mureo ; Egawa, Hiroto ; Takada, Yasutsugu ; Kaido, Toshimi ; Hatano, Etsuro ; Nguyen, Justin H ; Chen, Feng ; Baine, Ann Marie T ; Uemoto, Shinji. / Liver transplantation for congenital biliary dilatation : A single-center experience. In: Digestive Surgery. 2011 ; Vol. 27, No. 6. pp. 492-501.
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