Liver transplantation for acute liver failure

outcome analysis.

A. O. Shakil, I. Dvorchik, J. J. Fung, Jorge Rakela

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Acute liver failure (ALF) remains a major cause of morbidity and mortality. Before the availability of liver transplantation only 20% of patients with ALF survived. The clinical dilemma relates to the prognostication of these patients, as early liver transplantation has been associated with better outcomes. The eligibility for liver transplantation must therefore be quickly established. The patient's age, aetiology of disease, interval between the onset of jaundice and encephalopathy, blood pH, prothrombin time, serum bilirubin and serum creatinine levels has been identified as useful prognostic markers. The degree of hepatocyte necrosis on liver biopsy and estimated hepatic volume by computed tomography may also be valuable predictors of survival; however, further studies are needed.

Original languageEnglish (US)
Pages (from-to)107-110
Number of pages4
JournalJournal of Viral Hepatitis
Volume4 Suppl 1
StatePublished - 1997
Externally publishedYes

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Acute Liver Failure
Liver Transplantation
Cone-Beam Computed Tomography
Liver
Prothrombin Time
Brain Diseases
Jaundice
Serum
Bilirubin
Hepatocytes
Creatinine
Necrosis
Morbidity
Biopsy
Survival
Mortality

ASJC Scopus subject areas

  • Hepatology
  • Virology

Cite this

Shakil, A. O., Dvorchik, I., Fung, J. J., & Rakela, J. (1997). Liver transplantation for acute liver failure: outcome analysis. Journal of Viral Hepatitis, 4 Suppl 1, 107-110.

Liver transplantation for acute liver failure : outcome analysis. / Shakil, A. O.; Dvorchik, I.; Fung, J. J.; Rakela, Jorge.

In: Journal of Viral Hepatitis, Vol. 4 Suppl 1, 1997, p. 107-110.

Research output: Contribution to journalArticle

Shakil, AO, Dvorchik, I, Fung, JJ & Rakela, J 1997, 'Liver transplantation for acute liver failure: outcome analysis.', Journal of Viral Hepatitis, vol. 4 Suppl 1, pp. 107-110.
Shakil, A. O. ; Dvorchik, I. ; Fung, J. J. ; Rakela, Jorge. / Liver transplantation for acute liver failure : outcome analysis. In: Journal of Viral Hepatitis. 1997 ; Vol. 4 Suppl 1. pp. 107-110.
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