Liver Transplantation: Early and Long Term Management and Complications

Chakri Panjala, Denise M. Harnois

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Post liver transplantation care begins with immunosuppression induction and maintenance and continues with close monitoring of graft function as well as renal, metabolic and infectious diseases complications. A number of recipient, donor and operative factors influence post-operative complications. Neurogenic, cardiovascular, renal, gastrointestinal and metabolic side effects may manifest early or later in the post-transplant period, while primary disease recurrence and malignancy issues most often manifest later in the course. With improvement in survival rates after liver transplantation, due to advances in surgical techniques and immunosuppression drugs, non-transplant related causes like cardiovascular disease and de novo malignancies are becoming responsible for most late deaths in the recipients. Liver transplant recipients hence require a multi-disciplinary team approach from day one after the transplant followed by a tailored screening and health maintenance regimen.

Original languageEnglish (US)
Title of host publicationPractical Gastroenterology and Hepatology
Subtitle of host publicationLiver and Biliary Disease
PublisherWiley-Blackwell
Pages327-346
Number of pages20
ISBN (Print)9781405182751
DOIs
StatePublished - Aug 31 2010

Keywords

  • Acute Renal Failure
  • Biliary Complications
  • Cardiovascular Complications
  • Chronic Kidney Disease
  • Infectious Diseases Complications
  • Neurologic Complications
  • Vascular Complications

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Panjala, C., & Harnois, D. M. (2010). Liver Transplantation: Early and Long Term Management and Complications. In Practical Gastroenterology and Hepatology: Liver and Biliary Disease (pp. 327-346). Wiley-Blackwell. https://doi.org/10.1002/9781444325249.ch32