TY - JOUR
T1 - Live donor liver transplantation for alcoholic hepatitis
AU - Singal, Ashwani K.
AU - Kamath, Patrick Sequeira
PY - 2016/10/6
Y1 - 2016/10/6
N2 - Liver transplantation is a definitive therapy for patients with end-stage liver disease and cirrhosis, with improvement in survival and quality of life. Patients are carefully screened and selected for this modality of treatment to achieve maximum survival benefit. For example, a patient with hepatocellular carcinoma is a candidate if he or she is within Milan criteria and has no significant comorbidity. Similarly, patients with alcoholic cirrhosis are transplant candidates if they are deemed to have been rehabilitated from abusive alcohol consumption and are at low risk for recidivism. More recently, carefully selected patients with alcoholic hepatitis have been successfully transplanted. The preferred transplantation modality is cadaveric liver transplantation. However, living donor liver transplantation is carried out if there is no cadaveric liver organ allocation system, or if the patient is deemed to be at low priority for cadaveric organ transplantation based on the allocation system. Living donor liver transplantation for alcoholic hepatitis needs to be addressed with this background in mind.
AB - Liver transplantation is a definitive therapy for patients with end-stage liver disease and cirrhosis, with improvement in survival and quality of life. Patients are carefully screened and selected for this modality of treatment to achieve maximum survival benefit. For example, a patient with hepatocellular carcinoma is a candidate if he or she is within Milan criteria and has no significant comorbidity. Similarly, patients with alcoholic cirrhosis are transplant candidates if they are deemed to have been rehabilitated from abusive alcohol consumption and are at low risk for recidivism. More recently, carefully selected patients with alcoholic hepatitis have been successfully transplanted. The preferred transplantation modality is cadaveric liver transplantation. However, living donor liver transplantation is carried out if there is no cadaveric liver organ allocation system, or if the patient is deemed to be at low priority for cadaveric organ transplantation based on the allocation system. Living donor liver transplantation for alcoholic hepatitis needs to be addressed with this background in mind.
KW - Liver donor
KW - Liver transplantation
UR - http://www.scopus.com/inward/record.url?scp=84990866193&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84990866193&partnerID=8YFLogxK
U2 - 10.1007/s12072-016-9770-1
DO - 10.1007/s12072-016-9770-1
M3 - Article
C2 - 27714680
AN - SCOPUS:84990866193
SP - 1
EP - 4
JO - Hepatology International
JF - Hepatology International
SN - 1936-0533
ER -