Lipoprotein analysis in the evaluation of chest pain in the emergency department

P. C. Gay, R. A. Nishimura, C. S. Roth, W. E. Evans, A. R. Zinsmeister, B. A. Kottke

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Apolipoproteins were measured in a prospective blinded fashion in blood specimens from patients with chest pain in the emergency department. A definitive diagnosis for the chest pain (non-cardiac-related in 32% and angina or myocardial infarction in 68%) was available in 136 of the 162 patients originally enrolled in the study. Logistic regression and multivariate analysis failed to show any usefulness of apolipoprotein determinations in distinguishing patients with cardiac ischemia from those without it. The clinician's initial impression of the chest pain, the electrocardiogram, a history of previous angina, myocardial infarction, or peripheral atherosclerosis, and male sex were strongly associated with the final diagnosis. We conclude that, although apolipoprotein analysis has proved useful in epidemiologic studies, the most reliable indicators of ischemic pain remain the medical history, the electrocardiogram, and the clinician's overall initial impression.

Original languageEnglish (US)
Pages (from-to)885-891
Number of pages7
JournalMayo Clinic Proceedings
Volume66
Issue number9
StatePublished - 1991

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Apolipoproteins
Chest Pain
Lipoproteins
Hospital Emergency Service
Electrocardiography
Myocardial Infarction
Epidemiologic Studies
Atherosclerosis
Multivariate Analysis
Ischemia
Logistic Models
Regression Analysis
Pain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gay, P. C., Nishimura, R. A., Roth, C. S., Evans, W. E., Zinsmeister, A. R., & Kottke, B. A. (1991). Lipoprotein analysis in the evaluation of chest pain in the emergency department. Mayo Clinic Proceedings, 66(9), 885-891.

Lipoprotein analysis in the evaluation of chest pain in the emergency department. / Gay, P. C.; Nishimura, R. A.; Roth, C. S.; Evans, W. E.; Zinsmeister, A. R.; Kottke, B. A.

In: Mayo Clinic Proceedings, Vol. 66, No. 9, 1991, p. 885-891.

Research output: Contribution to journalArticle

Gay, PC, Nishimura, RA, Roth, CS, Evans, WE, Zinsmeister, AR & Kottke, BA 1991, 'Lipoprotein analysis in the evaluation of chest pain in the emergency department', Mayo Clinic Proceedings, vol. 66, no. 9, pp. 885-891.
Gay PC, Nishimura RA, Roth CS, Evans WE, Zinsmeister AR, Kottke BA. Lipoprotein analysis in the evaluation of chest pain in the emergency department. Mayo Clinic Proceedings. 1991;66(9):885-891.
Gay, P. C. ; Nishimura, R. A. ; Roth, C. S. ; Evans, W. E. ; Zinsmeister, A. R. ; Kottke, B. A. / Lipoprotein analysis in the evaluation of chest pain in the emergency department. In: Mayo Clinic Proceedings. 1991 ; Vol. 66, No. 9. pp. 885-891.
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