Lipid metabolism greases the stem cell engine

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Metabolic plasticity is increasingly postulated to be vital in the transition between stemness maintenance and lineage specification. Knobloch et al. (2012) now demonstrate that regulation of lipogenesis by fatty acid synthase and Spot14-dependent malonyl-CoA supply determines the proliferative activity of resident neural stem cells, contributing to adult neurogenesis.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalCell Metabolism
Volume17
Issue number2
DOIs
StatePublished - Feb 5 2013

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Malonyl Coenzyme A
Fatty Acid Synthases
Lipogenesis
Neural Stem Cells
Neurogenesis
Lipid Metabolism
Stem Cells
Maintenance

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Physiology

Cite this

Lipid metabolism greases the stem cell engine. / Folmes, Clifford; Park, Sungjo; Terzic, Andre.

In: Cell Metabolism, Vol. 17, No. 2, 05.02.2013, p. 153-155.

Research output: Contribution to journalArticle

Folmes, Clifford ; Park, Sungjo ; Terzic, Andre. / Lipid metabolism greases the stem cell engine. In: Cell Metabolism. 2013 ; Vol. 17, No. 2. pp. 153-155.
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