Lipid metabolism greases the stem cell engine

Research output: Contribution to journalShort surveypeer-review

29 Scopus citations

Abstract

Metabolic plasticity is increasingly postulated to be vital in the transition between stemness maintenance and lineage specification. Knobloch et al. (2012) now demonstrate that regulation of lipogenesis by fatty acid synthase and Spot14-dependent malonyl-CoA supply determines the proliferative activity of resident neural stem cells, contributing to adult neurogenesis.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalCell Metabolism
Volume17
Issue number2
DOIs
StatePublished - Feb 5 2013

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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