Abstract
Metabolic plasticity is increasingly postulated to be vital in the transition between stemness maintenance and lineage specification. Knobloch et al. (2012) now demonstrate that regulation of lipogenesis by fatty acid synthase and Spot14-dependent malonyl-CoA supply determines the proliferative activity of resident neural stem cells, contributing to adult neurogenesis.
Original language | English (US) |
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Pages (from-to) | 153-155 |
Number of pages | 3 |
Journal | Cell Metabolism |
Volume | 17 |
Issue number | 2 |
DOIs | |
State | Published - Feb 5 2013 |
ASJC Scopus subject areas
- Physiology
- Molecular Biology
- Cell Biology