Linear accelerator-based single-fraction stereotactic body radiotherapy for symptomatic vertebral body hemangiomas: The Mayo Clinic experience

Nathan Y. Yu, Terence T. Sio, Mark K. Lyons, Sujay A. Vora, Ali Turkmani, Paul D. Brown, Sean S. Park, James L. Leenstra, Bernard R. Bendok, Steven E. Schild, Jonathan B. Ashman

Research output: Contribution to journalArticle

Abstract

Symptomatic vertebral hemangiomas (SVHs) are rare benign tumors that when symptomatic require procedural intervention or radiotherapy (RT). Although conventionally-fractionated RT has been an alternative to surgical resection, there is very little data on stereotactic body radiotherapy (SBRT) for SVHs. Six consecutively treated patients with SVHs underwent definitive single-fraction SBRT from 2010 to 2018 at our institution. The RT planning parameters, treatment, outcome, and toxicities are reported for 6 patients with 6 total SVHs treated with single-fraction SBRT. Each patient presented with back pain and received single-fraction SBRT to a thoracic vertebral body hemangioma. One patient had received radiofrequency ablation prior to SBRT. The median SBRT dose was 18 Gy (range, 13–20). Following SBRT, 4 (67%) patients reported improvement in presenting symptoms and 2 patients (33%) were refractory. There were no acute or chronic toxicities associated with SBRT including esophagitis, vertebral compression fractures, or myelopathy. To date, this is the largest series of single-fraction SBRT for SVHs. Single fraction SBRT appears to be a feasible option for SVHs. Further studies are needed to confirm our preliminary findings and optimize dose fractionation.

Original languageEnglish (US)
Pages (from-to)74-78
Number of pages5
JournalJournal of Clinical Neuroscience
Volume80
DOIs
StatePublished - Oct 2020

Keywords

  • Hemangioma
  • Linear accelerator
  • SBRT
  • Spine hemangioma
  • Stereotactic body radiotherapy
  • Symptomatic vertebral hemangioma
  • Vertebral hemangioma

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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