Leptomeningeal artery atherosclerosis visualized by angiography: clinical correlates

David S Knopman, D. C. Anderson, A. Mastri, D. Larson

Research output: Contribution to journalArticle

Abstract

Circumscribed atherosclerotic involvement of secondary and tertiary branches of major cerebral arteries is a common angiographic finding whose nature is rarely in question. However, widespread and severe changes are unusual, and radiologic interpretation may be more difficult. The authors recently cared for a patient whose angiogram demonstrated extensive involvement of leptomeningeal vessels and were prompted to review the clinical courses and autopsy findings of a number of other patients with similar angiographic findings. Their observations suggest that the radiological appearance of leptomeningeal artery atherosclerosis can be confused with that of an arteritis. Atherosclerosis of leptomeningeal arteries is strongly associated with a history of arterial hypertension and seems to parallel arterial lesions thought responsible for lacunar infarction and intraparenchymal hemorrhage.

Original languageEnglish (US)
Pages (from-to)262-266
Number of pages5
JournalStroke
Volume9
Issue number3
StatePublished - 1978
Externally publishedYes

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Atherosclerosis
Angiography
Arteries
Lacunar Stroke
Arteritis
Cerebral Arteries
Autopsy
Hemorrhage
Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Knopman, D. S., Anderson, D. C., Mastri, A., & Larson, D. (1978). Leptomeningeal artery atherosclerosis visualized by angiography: clinical correlates. Stroke, 9(3), 262-266.

Leptomeningeal artery atherosclerosis visualized by angiography : clinical correlates. / Knopman, David S; Anderson, D. C.; Mastri, A.; Larson, D.

In: Stroke, Vol. 9, No. 3, 1978, p. 262-266.

Research output: Contribution to journalArticle

Knopman, DS, Anderson, DC, Mastri, A & Larson, D 1978, 'Leptomeningeal artery atherosclerosis visualized by angiography: clinical correlates', Stroke, vol. 9, no. 3, pp. 262-266.
Knopman, David S ; Anderson, D. C. ; Mastri, A. ; Larson, D. / Leptomeningeal artery atherosclerosis visualized by angiography : clinical correlates. In: Stroke. 1978 ; Vol. 9, No. 3. pp. 262-266.
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