Leiomyoma of the female urethra and bladder: Report of twenty-three patients and review of the literature

J. L. Cornella, T. R. Larson, R. A. Lee, J. F. Magrina, D. Kemmerer-Doak, G. E. Hayden, P. N. Fuller, E. A. Gates, J. J. Klutke

Research output: Contribution to journalArticlepeer-review

107 Scopus citations


OBJECTIVES: Our purpose was to review what may be the largest experience of bladder and urethral leiomyomas from a single institution. STUDY DESIGN: A retrospective review was done of 23 female patients with emphasis on presentation, symptoms, and operative approach for excision. RESULTS: The majority of bladder and urethral leiomyomas in this series were asymptomatic, nonobstructive, or incidental (discovered at surgery for another entity). Ten patients had a palpable mass on physical examination. Two patients had pain as a presenting complaint. The route of operative excision was transvaginal (10 patients), transurethral leiomyoma removed elsewhere with a resultant vesicovaginal fistula. CONCLUSIONS: Corollaries should be sought with the experience of uterine leiomyomas, which are histologically identical to bladder leiomyomas. Asymptomatic, nonobstructive, and nonproblematic leiomyomas should not serve as an indication for primary operation. Pedunculated endovesical lesions may be an exception because of the ease of transurethral removal and their tendency to cause future symptoms. Ultrasonographic imaging, cystoscopy, and biopsy should be considered to allow observation and follow-up of leiomyomas. Future investigative cytogenetic studies should be considered on these mesenchymal tumors.

Original languageEnglish (US)
Pages (from-to)1278-1285
Number of pages8
JournalAmerican journal of obstetrics and gynecology
Issue number6
StatePublished - 1997


  • Bladder leiomyoma
  • Leiomyoma
  • Urethral leiomyoma

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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