Left atrial appendage dysfunction in a patient with premature ventricular contractions - A risk factor for stroke?

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3 Scopus citations

Abstract

A 16-year-old female with ventricular dysfunction and frequent ventricular arrhythmia presented with a cardioembolic stroke. Prior electrophysiology study and ablation was performed for ventricular tachycardia (VT). For remaining ventricular ectopy, the patient was maintained on carvedilol and mexiletine. After one year on this regimen, she presented with an acute stroke. Transesophageal echocardiography revealed no evidence of an intracardiac or ventricular thrombus but demonstrated markedly decreased left atrial appendage (LAA) flow velocity worsened during frequent premature ventricular contractions (PVC). In the absence of atrial fibrillation (AF), the LAA dysfunction was considered secondary to the frequent PVCs and was thought to be the underlying cause for the stroke. We present this case to highlight a potential under recognized association between LAA dysfunction and ventricular arrhythmia, similar to that observed with atrioventricular dyssynchronous pacing.

Original languageEnglish (US)
Pages (from-to)136-141
Number of pages6
JournalIndian Pacing and Electrophysiology Journal
Volume13
Issue number4
DOIs
StatePublished - 2013

Keywords

  • Left atrial appendage
  • Noncompaction cardiomyopathy
  • PVC
  • Risk
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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