Late recurrence and rapid evolution of severe hepatopulmonary syndrome after liver transplantation

M. J. Krowka; G. A. Wiseman; J. L. Steers; R. H. Wiesner

doi:10.1002/lt.500050502

Late recurrence and rapid evolution of severe hepatopulmonary syndrome after liver transplantation

M. J. Krowka, G. A. Wiseman, J. L. Steers, R. H. Wiesner

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21 Scopus citations

Abstract

Recurrence of hepatopulmonary syndrome (HPS) after orthotopic liver transplantation (OLT) in an adult has never been reported. We describe a 23- year-old woman who initially underwent OLT because of debilitating and severe HPS associated with nonalcoholic steatohepatitis (NASH). Although the clinical resolution of HPS was well documented day 117 post-OLT, the reappearance of NASH was documented by liver biopsy. Severe hypoxemia because of recurrent HPS rapidly evolved beginning approximately day 700 post-OLT. Retransplantation was attempted, but the patient died post-OLT of sepsis and/or multiorgan failure.

Original language	English (US)
Pages (from-to)	451-453
Number of pages	3
Journal	Liver Transplantation and Surgery
Volume	5
Issue number	5
DOIs	https://doi.org/10.1002/lt.500050502
State	Published - 1999

ASJC Scopus subject areas

Surgery
Hepatology

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abstract = "Recurrence of hepatopulmonary syndrome (HPS) after orthotopic liver transplantation (OLT) in an adult has never been reported. We describe a 23- year-old woman who initially underwent OLT because of debilitating and severe HPS associated with nonalcoholic steatohepatitis (NASH). Although the clinical resolution of HPS was well documented day 117 post-OLT, the reappearance of NASH was documented by liver biopsy. Severe hypoxemia because of recurrent HPS rapidly evolved beginning approximately day 700 post-OLT. Retransplantation was attempted, but the patient died post-OLT of sepsis and/or multiorgan failure.",

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AU - Krowka, M. J.

AU - Wiseman, G. A.

AU - Steers, J. L.

AU - Wiesner, R. H.

PY - 1999

Y1 - 1999

N2 - Recurrence of hepatopulmonary syndrome (HPS) after orthotopic liver transplantation (OLT) in an adult has never been reported. We describe a 23- year-old woman who initially underwent OLT because of debilitating and severe HPS associated with nonalcoholic steatohepatitis (NASH). Although the clinical resolution of HPS was well documented day 117 post-OLT, the reappearance of NASH was documented by liver biopsy. Severe hypoxemia because of recurrent HPS rapidly evolved beginning approximately day 700 post-OLT. Retransplantation was attempted, but the patient died post-OLT of sepsis and/or multiorgan failure.

AB - Recurrence of hepatopulmonary syndrome (HPS) after orthotopic liver transplantation (OLT) in an adult has never been reported. We describe a 23- year-old woman who initially underwent OLT because of debilitating and severe HPS associated with nonalcoholic steatohepatitis (NASH). Although the clinical resolution of HPS was well documented day 117 post-OLT, the reappearance of NASH was documented by liver biopsy. Severe hypoxemia because of recurrent HPS rapidly evolved beginning approximately day 700 post-OLT. Retransplantation was attempted, but the patient died post-OLT of sepsis and/or multiorgan failure.

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Late recurrence and rapid evolution of severe hepatopulmonary syndrome after liver transplantation

Abstract

ASJC Scopus subject areas

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