Large Symptomatic Carotid Body Tumor Resection Aided by Preoperative Embolization and Mandibular Subluxation

Alessandra Puggioni, Konstantinos T. Delis, Charles E. Fields, Christopher F. Viozzi, David F. Kallmes, Peter Gloviczki

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Carotid body tumors (CBT) are rare and usually benign neoplasms (60%-90%), originating from the mesoderm and neural ectoderm. In view of the extensive and unrelenting growth of unresected CBT, encasing vital neurovascular structures, and the significant incidence of malignancy (>10%), surgical excision is the standard treatment of choice. Despite progress in CBT imaging and surgical technique, cranial nerve deficit, stroke, and death continue to affect 10% to 40% of patients undergoing curative surgical resection, particularly in large tumors proximal to the skull base. In such cases, CBT shrinkage by preoperative embolization, improved surgical access utilizing mandibular subluxation, and electroencephalographic monitoring combined with meticulous surgical technique may enable curative tumor resection, without prohibitive morbidity. In light of associated disability, preoperative acknowledgment of the ever-present substantial risk of cranial nerve injury cannot be overemphasized. We report on a patient with a large symptomatic CBT treated surgically with the aid of mandibular subluxation and preoperative embolization.

Original languageEnglish (US)
Pages (from-to)21-28
Number of pages8
JournalPerspectives in Vascular Surgery and Endovascular Therapy
Volume17
Issue number1
DOIs
StatePublished - Mar 2005

Keywords

  • carotid body tumors
  • embolization
  • mandibular subluxation

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Large Symptomatic Carotid Body Tumor Resection Aided by Preoperative Embolization and Mandibular Subluxation'. Together they form a unique fingerprint.

  • Cite this