Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant: a Matched Case-Control Study

Levan Tsamalaidze, John A. Stauffer, Lisa C. Arasi, Diego E. Villacreses, Jose Salvador Serrano Franco, Steven Bowers, Enrique F. Elli

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Introduction: Obesity is frequently encountered in patients with orthotopic liver transplant (OLT). The role of bariatric surgery is still unclear for this specific population. The aim of this study was to review our experience with laparoscopic sleeve gastrectomy (LSG) after OLT. Material and Methods: We performed a retrospective case-control study of patients undergoing LSG after OLT from 2010 to 2016. OLT-LSG patients were matched by age, sex, body mass index (BMI), and year to non-OLT patients undergoing LSG. Demographics, operative variables, postoperative events, and long-term weight loss with comorbidity resolution were collected and compared between cases and controls. Results: Of 303 patients undergoing LSG, 12 (4%) had previous OLT. They were matched to 36 non-OLT patients. No difference was found between groups in the American Society of Anesthesiologists class, mean operative time, or postoperative morbidity. The non-OLT group, however, had a significantly shorter mean hospital stay than the OLT group (1.7 vs 3.1 days; P < .001). There were no conversions to open procedures. For patients with long-term follow-up, change in BMI after LSG was similar between the groups, but the non-OLT patients had significantly more excess body weight loss at 2 years (53.7 vs 45.2%; P < .001). Similar resolution of comorbid conditions was noted in both groups. LSG caused no changes in dosage of immunosuppressive medications, and no liver complications occurred. Conclusion: LSG after OLT in appropriately selected patients appears to have similar outcomes to LSG in non-OLT patients.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalObesity Surgery
DOIs
StateAccepted/In press - Aug 1 2017

Fingerprint

Morbid Obesity
Gastrectomy
Case-Control Studies
Transplants
Liver
Weight Loss
Body Mass Index
Conversion to Open Surgery
Bariatric Surgery
Immunosuppressive Agents
Operative Time
Comorbidity
Length of Stay
Obesity

Keywords

  • Bariatric surgery
  • Laparoscopic sleeve gastrectomy
  • Orthotopic liver transplant

ASJC Scopus subject areas

  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

Tsamalaidze, L., Stauffer, J. A., Arasi, L. C., Villacreses, D. E., Franco, J. S. S., Bowers, S., & Elli, E. F. (Accepted/In press). Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant: a Matched Case-Control Study. Obesity Surgery, 1-7. https://doi.org/10.1007/s11695-017-2847-7

Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant : a Matched Case-Control Study. / Tsamalaidze, Levan; Stauffer, John A.; Arasi, Lisa C.; Villacreses, Diego E.; Franco, Jose Salvador Serrano; Bowers, Steven; Elli, Enrique F.

In: Obesity Surgery, 01.08.2017, p. 1-7.

Research output: Contribution to journalArticle

Tsamalaidze, Levan ; Stauffer, John A. ; Arasi, Lisa C. ; Villacreses, Diego E. ; Franco, Jose Salvador Serrano ; Bowers, Steven ; Elli, Enrique F. / Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant : a Matched Case-Control Study. In: Obesity Surgery. 2017 ; pp. 1-7.
@article{dbb2500f46b64becbbe1c01cfbf3409c,
title = "Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant: a Matched Case-Control Study",
abstract = "Introduction: Obesity is frequently encountered in patients with orthotopic liver transplant (OLT). The role of bariatric surgery is still unclear for this specific population. The aim of this study was to review our experience with laparoscopic sleeve gastrectomy (LSG) after OLT. Material and Methods: We performed a retrospective case-control study of patients undergoing LSG after OLT from 2010 to 2016. OLT-LSG patients were matched by age, sex, body mass index (BMI), and year to non-OLT patients undergoing LSG. Demographics, operative variables, postoperative events, and long-term weight loss with comorbidity resolution were collected and compared between cases and controls. Results: Of 303 patients undergoing LSG, 12 (4{\%}) had previous OLT. They were matched to 36 non-OLT patients. No difference was found between groups in the American Society of Anesthesiologists class, mean operative time, or postoperative morbidity. The non-OLT group, however, had a significantly shorter mean hospital stay than the OLT group (1.7 vs 3.1 days; P < .001). There were no conversions to open procedures. For patients with long-term follow-up, change in BMI after LSG was similar between the groups, but the non-OLT patients had significantly more excess body weight loss at 2 years (53.7 vs 45.2{\%}; P < .001). Similar resolution of comorbid conditions was noted in both groups. LSG caused no changes in dosage of immunosuppressive medications, and no liver complications occurred. Conclusion: LSG after OLT in appropriately selected patients appears to have similar outcomes to LSG in non-OLT patients.",
keywords = "Bariatric surgery, Laparoscopic sleeve gastrectomy, Orthotopic liver transplant",
author = "Levan Tsamalaidze and Stauffer, {John A.} and Arasi, {Lisa C.} and Villacreses, {Diego E.} and Franco, {Jose Salvador Serrano} and Steven Bowers and Elli, {Enrique F.}",
year = "2017",
month = "8",
day = "1",
doi = "10.1007/s11695-017-2847-7",
language = "English (US)",
pages = "1--7",
journal = "Obesity Surgery",
issn = "0960-8923",
publisher = "Springer New York",

}

TY - JOUR

T1 - Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant

T2 - a Matched Case-Control Study

AU - Tsamalaidze, Levan

AU - Stauffer, John A.

AU - Arasi, Lisa C.

AU - Villacreses, Diego E.

AU - Franco, Jose Salvador Serrano

AU - Bowers, Steven

AU - Elli, Enrique F.

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Introduction: Obesity is frequently encountered in patients with orthotopic liver transplant (OLT). The role of bariatric surgery is still unclear for this specific population. The aim of this study was to review our experience with laparoscopic sleeve gastrectomy (LSG) after OLT. Material and Methods: We performed a retrospective case-control study of patients undergoing LSG after OLT from 2010 to 2016. OLT-LSG patients were matched by age, sex, body mass index (BMI), and year to non-OLT patients undergoing LSG. Demographics, operative variables, postoperative events, and long-term weight loss with comorbidity resolution were collected and compared between cases and controls. Results: Of 303 patients undergoing LSG, 12 (4%) had previous OLT. They were matched to 36 non-OLT patients. No difference was found between groups in the American Society of Anesthesiologists class, mean operative time, or postoperative morbidity. The non-OLT group, however, had a significantly shorter mean hospital stay than the OLT group (1.7 vs 3.1 days; P < .001). There were no conversions to open procedures. For patients with long-term follow-up, change in BMI after LSG was similar between the groups, but the non-OLT patients had significantly more excess body weight loss at 2 years (53.7 vs 45.2%; P < .001). Similar resolution of comorbid conditions was noted in both groups. LSG caused no changes in dosage of immunosuppressive medications, and no liver complications occurred. Conclusion: LSG after OLT in appropriately selected patients appears to have similar outcomes to LSG in non-OLT patients.

AB - Introduction: Obesity is frequently encountered in patients with orthotopic liver transplant (OLT). The role of bariatric surgery is still unclear for this specific population. The aim of this study was to review our experience with laparoscopic sleeve gastrectomy (LSG) after OLT. Material and Methods: We performed a retrospective case-control study of patients undergoing LSG after OLT from 2010 to 2016. OLT-LSG patients were matched by age, sex, body mass index (BMI), and year to non-OLT patients undergoing LSG. Demographics, operative variables, postoperative events, and long-term weight loss with comorbidity resolution were collected and compared between cases and controls. Results: Of 303 patients undergoing LSG, 12 (4%) had previous OLT. They were matched to 36 non-OLT patients. No difference was found between groups in the American Society of Anesthesiologists class, mean operative time, or postoperative morbidity. The non-OLT group, however, had a significantly shorter mean hospital stay than the OLT group (1.7 vs 3.1 days; P < .001). There were no conversions to open procedures. For patients with long-term follow-up, change in BMI after LSG was similar between the groups, but the non-OLT patients had significantly more excess body weight loss at 2 years (53.7 vs 45.2%; P < .001). Similar resolution of comorbid conditions was noted in both groups. LSG caused no changes in dosage of immunosuppressive medications, and no liver complications occurred. Conclusion: LSG after OLT in appropriately selected patients appears to have similar outcomes to LSG in non-OLT patients.

KW - Bariatric surgery

KW - Laparoscopic sleeve gastrectomy

KW - Orthotopic liver transplant

UR - http://www.scopus.com/inward/record.url?scp=85026517777&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026517777&partnerID=8YFLogxK

U2 - 10.1007/s11695-017-2847-7

DO - 10.1007/s11695-017-2847-7

M3 - Article

AN - SCOPUS:85026517777

SP - 1

EP - 7

JO - Obesity Surgery

JF - Obesity Surgery

SN - 0960-8923

ER -