Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation

Aaron D. Martin, Kristin L. Mekeel, Erik P Castle, Sneha S. Vaish, George L. Martin, Adyr A. Moss, David C. Mulligan, Raymond L. Heilman, Kunam Sudhakar Reddy, Paul E. Andrews

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

OBJECTIVE • To analyse the perioperative outcomes of native bilateral laparoscopic nephrectomy (BLN) with simultaneous kidney transplantation. PATIENTS AND METHODS • From November 2000 to April 2011, 37 patients were seen for renal failure secondary to autosomal-dominant polycystic kidney disease (ADPKD) and underwent renal transplant with native nephrectomies at a single tertiary academic centre. • In all, 15 patients underwent BLN for ADPKD followed by simultaneous kidney transplantation. • The other 22 patients underwent BLN for ADPKD with kidney transplant performed at a separate setting. • Demographic data, perioperative outcomes, complications regardless of need for intervention, and graft function were analysed in both groups. RESULTS • The combined surgery was completed without intraoperative complication in all cases. • The median total operative duration was 372 min, estimated blood loss was 300 mL with two patients requiring transfusion, and the median (range) hospital stay was 5 (3-7) days. • All patients had immediate graft function with additional relief of compressive symptoms. • In comparison to our staged cohort, the simultaneous group had a significantly shorter total hospital stay. • All other outcomes and complication rates were comparable. CONCLUSION • In ADPKD, a less invasive laparoscopic approach for native nephrectomies with simultaneous renal transplant offers comparable morbidity without graft compromise and the convenience of one operation and one recovery for the patient.

Original languageEnglish (US)
JournalBJU International
Volume110
Issue number11 C
DOIs
StatePublished - Dec 2012

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Nephrectomy
Kidney Transplantation
Autosomal Dominant Polycystic Kidney
Transplants
Kidney
Length of Stay
Intraoperative Complications
Renal Insufficiency
Demography
Morbidity

Keywords

  • ADPKD
  • Laparoscopy
  • Minimally invasive surgery
  • Nephrectomy
  • Renal transplant

ASJC Scopus subject areas

  • Urology

Cite this

Martin, A. D., Mekeel, K. L., Castle, E. P., Vaish, S. S., Martin, G. L., Moss, A. A., ... Andrews, P. E. (2012). Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation. BJU International, 110(11 C). https://doi.org/10.1111/j.1464-410X.2012.11379.x

Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation. / Martin, Aaron D.; Mekeel, Kristin L.; Castle, Erik P; Vaish, Sneha S.; Martin, George L.; Moss, Adyr A.; Mulligan, David C.; Heilman, Raymond L.; Reddy, Kunam Sudhakar; Andrews, Paul E.

In: BJU International, Vol. 110, No. 11 C, 12.2012.

Research output: Contribution to journalArticle

Martin, AD, Mekeel, KL, Castle, EP, Vaish, SS, Martin, GL, Moss, AA, Mulligan, DC, Heilman, RL, Reddy, KS & Andrews, PE 2012, 'Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation', BJU International, vol. 110, no. 11 C. https://doi.org/10.1111/j.1464-410X.2012.11379.x
Martin, Aaron D. ; Mekeel, Kristin L. ; Castle, Erik P ; Vaish, Sneha S. ; Martin, George L. ; Moss, Adyr A. ; Mulligan, David C. ; Heilman, Raymond L. ; Reddy, Kunam Sudhakar ; Andrews, Paul E. / Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation. In: BJU International. 2012 ; Vol. 110, No. 11 C.
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AB - OBJECTIVE • To analyse the perioperative outcomes of native bilateral laparoscopic nephrectomy (BLN) with simultaneous kidney transplantation. PATIENTS AND METHODS • From November 2000 to April 2011, 37 patients were seen for renal failure secondary to autosomal-dominant polycystic kidney disease (ADPKD) and underwent renal transplant with native nephrectomies at a single tertiary academic centre. • In all, 15 patients underwent BLN for ADPKD followed by simultaneous kidney transplantation. • The other 22 patients underwent BLN for ADPKD with kidney transplant performed at a separate setting. • Demographic data, perioperative outcomes, complications regardless of need for intervention, and graft function were analysed in both groups. RESULTS • The combined surgery was completed without intraoperative complication in all cases. • The median total operative duration was 372 min, estimated blood loss was 300 mL with two patients requiring transfusion, and the median (range) hospital stay was 5 (3-7) days. • All patients had immediate graft function with additional relief of compressive symptoms. • In comparison to our staged cohort, the simultaneous group had a significantly shorter total hospital stay. • All other outcomes and complication rates were comparable. CONCLUSION • In ADPKD, a less invasive laparoscopic approach for native nephrectomies with simultaneous renal transplant offers comparable morbidity without graft compromise and the convenience of one operation and one recovery for the patient.

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