Abstract
Inter- and intra-rater agreement in assessing Interstitial Pulmonary Fibrosis (IPF) on CT scans is poor. Lack of approaches to understand the nuances of CT reconstruction parameters and their effect on patient scans hampers objective IPF quantification. In this paper, we propose an image analytic methodology to characterize the relationship between CT reconstruction parameters and IPF manifestation in scans. The raw data acquired from a patient was reconstructed with a combination of image thickness, interval and reconstruction kernels to derive 104 datasets. Quantitative and qualitative analyses were performed on the regional statistics computed in the neighborhood of each parenchymal voxel and for expert-chosen regions of interest (ROIs). The proposed approach could facilitate the selection of optimal CT reconstruction parameters to more robustly quantify IPF.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings - International Symposium on Biomedical Imaging |
| Pages | 374-377 |
| Number of pages | 4 |
| DOIs | |
| State | Published - 2013 |
| Event | 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States Duration: Apr 7 2013 → Apr 11 2013 |
Other
| Other | 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 4/7/13 → 4/11/13 |
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Keywords
- classification
- Diffuse Parenchymal Lung Disease (DPLD)
- Interstitial Pulmonary Fibrosis (IPF)
- reconstruction kernel
- slice thickness
ASJC Scopus subject areas
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging
Cite this
Landscaping the effect of CT reconstruction parameters : Robust Interstitial Pulmonary Fibrosis quantitation. / Raghunath, S.; Rajagopalan, S.; Karwoski, R. A.; Bruesewitz, M. R.; McCollough, Cynthia H; Bartholmai, Brian Jack; Robb, R. A.
Proceedings - International Symposium on Biomedical Imaging. 2013. p. 374-377 6556490.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Landscaping the effect of CT reconstruction parameters
T2 - Robust Interstitial Pulmonary Fibrosis quantitation
AU - Raghunath, S.
AU - Rajagopalan, S.
AU - Karwoski, R. A.
AU - Bruesewitz, M. R.
AU - McCollough, Cynthia H
AU - Bartholmai, Brian Jack
AU - Robb, R. A.
PY - 2013
Y1 - 2013
N2 - Inter- and intra-rater agreement in assessing Interstitial Pulmonary Fibrosis (IPF) on CT scans is poor. Lack of approaches to understand the nuances of CT reconstruction parameters and their effect on patient scans hampers objective IPF quantification. In this paper, we propose an image analytic methodology to characterize the relationship between CT reconstruction parameters and IPF manifestation in scans. The raw data acquired from a patient was reconstructed with a combination of image thickness, interval and reconstruction kernels to derive 104 datasets. Quantitative and qualitative analyses were performed on the regional statistics computed in the neighborhood of each parenchymal voxel and for expert-chosen regions of interest (ROIs). The proposed approach could facilitate the selection of optimal CT reconstruction parameters to more robustly quantify IPF.
AB - Inter- and intra-rater agreement in assessing Interstitial Pulmonary Fibrosis (IPF) on CT scans is poor. Lack of approaches to understand the nuances of CT reconstruction parameters and their effect on patient scans hampers objective IPF quantification. In this paper, we propose an image analytic methodology to characterize the relationship between CT reconstruction parameters and IPF manifestation in scans. The raw data acquired from a patient was reconstructed with a combination of image thickness, interval and reconstruction kernels to derive 104 datasets. Quantitative and qualitative analyses were performed on the regional statistics computed in the neighborhood of each parenchymal voxel and for expert-chosen regions of interest (ROIs). The proposed approach could facilitate the selection of optimal CT reconstruction parameters to more robustly quantify IPF.
KW - classification
KW - Diffuse Parenchymal Lung Disease (DPLD)
KW - Interstitial Pulmonary Fibrosis (IPF)
KW - reconstruction kernel
KW - slice thickness
UR - http://www.scopus.com/inward/record.url?scp=84881623742&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881623742&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2013.6556490
DO - 10.1109/ISBI.2013.6556490
M3 - Conference contribution
AN - SCOPUS:84881623742
SN - 9781467364546
SP - 374
EP - 377
BT - Proceedings - International Symposium on Biomedical Imaging
ER -