Abstract
Lamins A and C are products of alternate splicing of one transcript from a single gene. We have isolated a partial cDNA, cE1-2, whose 800-bp sequence is 99% identical to the 3′ untranslated region of the lamin A/C gene. We report here the mapping of this gene and a closely related sequence to human chromosomes 1 and 10, more specifically, to 1q12.1-q23. The localization of cE1-2 hybridizing sequences to two different chromosomes suggests that one of these loci represents an as yet unknown member of the lamin gene family, either a pseudogene or an expressed gene.
Original language | English (US) |
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Pages (from-to) | 203-208 |
Number of pages | 6 |
Journal | Somatic Cell and Molecular Genetics |
Volume | 19 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1993 |
ASJC Scopus subject areas
- Genetics
- Cell Biology