Lack of Seasonal Differences in Basal Metabolic Rate in Humans

A Cross-Sectional Study

P. Anthanont, James A. Levine, S. K. Mccrady-Spitzer, Michael Dennis Jensen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Some studies indicate that basal metabolic rate is greater in winter than in the summer, suggesting a role for brown fat in human thermogenesis. We examined whether there are clinically meaningful differences in basal metabolic rate under thermoneutral conditions between winter and summer months in inhabitants of Rochester, Minnesota. We collated data from 220 research volunteers studied in the winter (December 1 – February 28) and 214 volunteers studied in the summer (June 1 – August 31), 1995–2012. Basal metabolic rate was measured by indirect calorimetry and body composition by dual-energy X-ray absorptiometry. The effect of season on basal metabolic rate was tested using multivariate regression analysis with basal metabolic rate as the dependent variable and fat-free mass, fat mass, age, sex, and season as the independent variables. The groups were comparable with respect to age, body mass index, fat mass, and fat-free mass. There was no significant difference in basal metabolic rate between winter and summer groups (1 667±322 vs. 1 669±330 kcal/day). Both winter and summer basal metabolic rates were strongly predicted by fat-free mass (Pearson’s r=0.75 and r=0.77, respectively, p <0.0001). Using multiple linear regression analysis, basal metabolic rate was significantly, independently predicted by fat-free mass, fat mass, age, and sex, but not season. We conclude that the lack of seasonal variation of thermoneutral basal metabolic rate between winter and summer suggests that modern, Western populations do not engage thermogenically detectable brown fat activity during periods of living in a cold climate.

Original languageEnglish (US)
JournalHormone and Metabolic Research
DOIs
StateAccepted/In press - Apr 27 2016

Fingerprint

Basal Metabolism
Cross-Sectional Studies
Fats
Brown Adipose Tissue
Regression analysis
Volunteers
Regression Analysis
Cold Climate
Indirect Calorimetry
Thermogenesis
Photon Absorptiometry
Calorimetry
Body Composition
Linear regression
Linear Models
Body Mass Index
Multivariate Analysis
X rays

Keywords

  • body composition
  • brown fat
  • indirect calorimetry

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Lack of Seasonal Differences in Basal Metabolic Rate in Humans : A Cross-Sectional Study. / Anthanont, P.; Levine, James A.; Mccrady-Spitzer, S. K.; Jensen, Michael Dennis.

In: Hormone and Metabolic Research, 27.04.2016.

Research output: Contribution to journalArticle

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