TY - JOUR
T1 - Lack of progression of neurologic deficit in survivors of paralytic polio
T2 - A 5-year prospective population-based study
AU - Windebank, Anthony J.
AU - Litchy, William J.
AU - Daube, Jasper R.
AU - Iverson, Rita A.
PY - 1996/1
Y1 - 1996/1
N2 - We completed a prospective, population-based cohort study of polio survivors in Olmsted County, Minnesota, between 1986 and 1993. We identified 50 individuals who had had paralytic polio between 1935 and 1960, as representative of all 300 cases of paralytic polio in the county. We completed detailed quantitative clinical and electrophysiologic studies at entry and after 5 years. These studies demonstrated stable neuromuscular function within the cohort, although 60% of the individuals were symptomatic. In two-thirds of the symptomatic patients, the causes of their symptoms were unrelated to earlier polio. For the 20% of patients who had unexplained muscle pain, perception of weakness, and fatigue, a mechanical disorder most likely underlies their symptoms.
AB - We completed a prospective, population-based cohort study of polio survivors in Olmsted County, Minnesota, between 1986 and 1993. We identified 50 individuals who had had paralytic polio between 1935 and 1960, as representative of all 300 cases of paralytic polio in the county. We completed detailed quantitative clinical and electrophysiologic studies at entry and after 5 years. These studies demonstrated stable neuromuscular function within the cohort, although 60% of the individuals were symptomatic. In two-thirds of the symptomatic patients, the causes of their symptoms were unrelated to earlier polio. For the 20% of patients who had unexplained muscle pain, perception of weakness, and fatigue, a mechanical disorder most likely underlies their symptoms.
UR - http://www.scopus.com/inward/record.url?scp=0029888794&partnerID=8YFLogxK
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U2 - 10.1212/WNL.46.1.80
DO - 10.1212/WNL.46.1.80
M3 - Article
C2 - 8559425
AN - SCOPUS:0029888794
SN - 0028-3878
VL - 46
SP - 80
EP - 84
JO - Neurology
JF - Neurology
IS - 1
ER -