Kluyvera co-infection in two solid organ transplant recipients: An emerging pathogen or a colonizer bystander?

R. Cheruvattath, V. Balan, R. Stewart, R. L. Heilman, D. C. Mulligan, S. Kusne

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Kluyvera species are opportunistic, gram-negative bacilli in the family Enterobacteriaceae. Ordinarily occurring as a commensal, Kluyvera have been reported to cause serious infections in immunosuppressed and immunocompetent hosts, causing diarrhea, urinary infections, peritonitis, and cholecystitis. We report Kluyvera infections in 2 solid organ transplant recipients. An 18-year-old female with alpha-1 antitrypsin deficiency underwent living donor liver transplantation and presented 6 months later with a liver abscess. The abscess aspirate grew mixed organisms including Kluyvera cryocrescens. A 22-year-old female with renal failure secondary to focal segmental glomerulosclerosis underwent a deceased donor kidney transplant and presented 3 months later with pyelonephritis; the urine culture grew Kluyvera ascorbata. Both patients improved only when their antibiotic coverage was broadened to include Kluyvera. The isolation of Kluyvera as a pathogen in transplant patients emphasizes that this commensal organism may be virulent in this patient population.

Original languageEnglish (US)
Pages (from-to)83-86
Number of pages4
JournalTransplant Infectious Disease
Issue number1
StatePublished - Mar 2007


  • Kidney transplant
  • Kluyvera infection
  • Liver transplant

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation


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