Kidney transplantation on extracorporeal life support for primary cardiac allograft dysfunction

Anthony N. Pham, Parag C. Patel, Kevin Landolfo, Justin M. Burns, Daniel S. Yip, Juan C. Leoni Moreno, Rohan M. Goswami, Samuel Jacob, Magdy M. El-Sayed Ahmed, Ian A. Makey, Mathew Thomas, Martin L. Mai, C. Burcin Taner, Si M. Pham

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Patients undergoing heart-kidney transplants who have primary graft dysfunction (PGD) of the heart are at risk of losing both organs, which may cause reluctance on the part of the transplant team to proceed with transplanting the kidney while the transplanted heart is being supported by mechanical device. We describe a case series in which 2 patients received kidney transplants while on veno-arterial ECMO support for PGD after heart transplant. Both patients are alive more than 1 year following transplant, with good cardiac and renal function and no signs of cardiac rejection. Kidney transplant surgery is safe for patients on veno-arterial ECMO support for cardiac PGD. It allows the heart recipient to receive a kidney from the same donor with both immunologic and survival advantages.

Original languageEnglish (US)
JournalJournal of Cardiac Surgery
DOIs
StateAccepted/In press - Jan 1 2020

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Keywords

  • extracorporeal membrane oxygenation
  • heart-kidney transplant
  • kidney transplant
  • primary graft dysfunction

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Pham, A. N., Patel, P. C., Landolfo, K., Burns, J. M., Yip, D. S., Leoni Moreno, J. C., Goswami, R. M., Jacob, S., El-Sayed Ahmed, M. M., Makey, I. A., Thomas, M., Mai, M. L., Taner, C. B., & Pham, S. M. (Accepted/In press). Kidney transplantation on extracorporeal life support for primary cardiac allograft dysfunction. Journal of Cardiac Surgery. https://doi.org/10.1111/jocs.14451