Kidney dysfunction and left ventricular assist device support: A comprehensive perioperative review

Samuel T. Coffin, Dia R. Waguespack, Nicholas A. Haglund, Simon Maltais, Jamie P. Dwyer, Mary E. Keebler

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Left ventricular assist devices (LVADs) are used increasingly as a bridge to transplantation or as destination therapy in end-stage heart failure patients who do not respond to optimal medical therapy. Many of these patients have end-organ dysfunction, including advanced kidney dysfunction, before and after LVAD implantation. Kidney dysfunction is a marker of adverse outcomes, such as increased morbidity and mortality. This review discusses kidney dysfunction and associated management strategies during the dynamic perioperative time period of LVAD implantation. Furthermore, we suggest potential future research directions to better understand the complex relationship between renal pathophysiology and mechanical circulatory support.

Original languageEnglish (US)
Pages (from-to)48-60
Number of pages13
JournalCardioRenal Medicine
Volume5
Issue number1
DOIs
StatePublished - Feb 24 2015

Keywords

  • Heart failure
  • Kidney injury
  • Ventricular assist device

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Urology

Fingerprint Dive into the research topics of 'Kidney dysfunction and left ventricular assist device support: A comprehensive perioperative review'. Together they form a unique fingerprint.

  • Cite this