Key emerging issues in progressive supranuclear palsy and corticobasal degeneration

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

It has been approximately 50 years since neurologists were introduced to the entities, “progressive supranuclear palsy” and “corticobasal degeneration”. Since the two seminal publications, there have been significant advancements in our understanding of these two neurodegenerative diseases, particularly the fact that both are associated with tau. Recent advances over the past 3 years that are notable to the field are discussed in this review that covers clinical diagnosis, pathological features, neuroimaging and CSF biomarkers, genetic associations and clinical trials related to progressive supranuclear palsy and corticobasal degeneration.

Original languageEnglish (US)
Pages (from-to)783-788
Number of pages6
JournalJournal of Neurology
Volume262
Issue number3
DOIs
StatePublished - Mar 18 2015

Keywords

  • CSF
  • Corticobasal
  • Davunetide
  • GWAS
  • Longitudinal
  • MRI
  • PSP
  • Tau
  • Tideglusib
  • Update

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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