Ketogenic Diet: an Endocrinologist Perspective

Aravind Reddy Kuchkuntla, Meera Shah, Saketh Velapati, Victoria M. Gershuni, Tamim Rajjo, Sanjeev Nanda, Ryan T. Hurt, Manpreet S. Mundi

Research output: Contribution to journalReview article

Abstract

Purpose of Review: Obesity and its related comorbidities make up a large part of healthcare expenditures. Despite a wide array of options for treatment of obesity, rates of sustained weight loss continue to be low, leading patients to seek alternative treatment options. Although the first medically utilized ketogenic diet was described nearly 100 years ago, it has made a resurgence as a treatment option for obesity. Despite increased popularity in the lay public and increased use of ketogenic dietary strategies for metabolic therapy, we are still beginning to unravel the metabolic impact of long-term dietary ketosis. Recent Findings: There are a number of recent trials that have highlighted the short- and long-term benefits of ketogenic diet on weight, glycemic control, and other endocrine functions including reproductive hormones. Summary: This review is a summary of available data on the effectiveness and durability of the ketogenic diet when compared to conventional interventions. Ketogenic dietary strategies may play a role in short-term improvement of important metabolic parameters with potential for long-term benefit. However, response may vary due to inter-individual ability to maintain long-term carbohydrate restriction.

Original languageEnglish (US)
Pages (from-to)402-410
Number of pages9
JournalCurrent nutrition reports
Volume8
Issue number4
DOIs
StatePublished - Dec 1 2019

Keywords

  • Diabetes
  • Ketogenic diet
  • Obesity
  • Weight loss

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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  • Cite this

    Kuchkuntla, A. R., Shah, M., Velapati, S., Gershuni, V. M., Rajjo, T., Nanda, S., Hurt, R. T., & Mundi, M. S. (2019). Ketogenic Diet: an Endocrinologist Perspective. Current nutrition reports, 8(4), 402-410. https://doi.org/10.1007/s13668-019-00297-x