KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA

Medicine & Life Sciences

• Heterotrimeric GTP-Binding Proteins 100%
• Monomeric GTP-Binding Proteins 88%
• Vascular Endothelial Growth Factor A 64%
• Cell Movement 61%
• Endothelial Cells 55%
• Human Umbilical Vein Endothelial Cells 22%
• Cell Proliferation 21%
• Gq-G11 GTP-Binding Protein alpha Subunits 16%
• Phosphorylation 14%
• Vascular Endothelial Growth Factor Receptor-1 14%
• Vascular Endothelial Growth Factor Receptor-2 13%
• Protein Subunits 12%
• Pertussis Toxin 12%
• Type C Phospholipases 11%
• Vascular Endothelium 11%
• Receptor Protein-Tyrosine Kinases 11%
• Phosphatidylinositol 3-Kinase 10%
• GTP-Binding Proteins 10%
• Mitogen-Activated Protein Kinases 10%
• ErbB Receptors 10%
• Down-Regulation 7%

Chemical Compounds

• Permeability 44%
• Protein 30%
• Tyrosine 17%