TY - JOUR
T1 - KDIGO Controversies Conference on onco-nephrology
T2 - kidney disease in hematological malignancies and the burden of cancer after kidney transplantation
AU - Conference Participants
AU - Małyszko, Jolanta
AU - Bamias, Aristotelis
AU - Danesh, Farhad R.
AU - Dębska-Ślizień, Alicja
AU - Gallieni, Maurizio
AU - Gertz, Morie A.
AU - Kielstein, Jan T.
AU - Tesarova, Petra
AU - Wong, Germaine
AU - Cheung, Michael
AU - Wheeler, David C.
AU - Winkelmayer, Wolfgang C.
AU - Porta, Camillo
AU - Abu-Alfa, Ali K.
AU - Amer, Hatem
AU - Beutel, Gernot
AU - Chapman, Jeremy
AU - Chen, Xiaohong
AU - Chudek, Jerzy
AU - Cosmai, Laura
AU - Danesi, Romano
AU - De Stefano, Filippo
AU - Iseki, Kunitoshi
AU - Jaimes, Edgar A.
AU - Jhaveri, Kenar D.
AU - Jurczyszyn, Artur
AU - Kazancioğlu, Rümeyza
AU - Kitchlu, Abhijat
AU - Kollmannsberger, Christian
AU - Lahoti, Amit
AU - Li, Yang
AU - Macía, Manuel
AU - Matsubara, Takeshi
AU - Mitropoulos, Dionysios
AU - Noiri, Eisei
AU - Perazella, Mark A.
AU - Ronco, Pierre
AU - Rosner, Mitchell H.
AU - Soler Romeo, Maria Jose
AU - Sprangers, Ben
AU - Stadler, Walter M.
AU - Stevens, Paul E.
AU - Tesař, Vladimír
AU - Torres da Costa e Silva, Verônica
AU - Vesole, David H.
AU - Vijayan, Anitha
AU - Viklický, Ondřej
AU - Workeneh, Biruh T.
AU - Yanagita, Motoko
AU - Zakharova, Elena
N1 - Publisher Copyright:
© 2020 Kidney Disease: Improving Global Outcomes (KDIGO)
PY - 2020/12
Y1 - 2020/12
N2 - The bidirectional relationship between cancer and chronic kidney disease (CKD) is complex. Patients with cancer, particularly those with hematological malignancies such as multiple myeloma and lymphoma, are at increased risk of developing acute kidney injury and CKD. On the other hand, emerging evidence from large observational registry analyses have consistently shown that cancer risk is increased by at least 2- to 3-fold in kidney transplant recipients, and the observed increased risk occurs not only in those who have received kidney transplants but also in those on dialysis and with mild- to moderate-stage CKD. The interactions between cancer and CKD have raised major therapeutic and clinical challenges in the management of these patients. Given the magnitude of the problem and uncertainties, and current controversies within the existing evidence, Kidney Disease: Improving Global Outcomes (KDIGO) assembled a global panel of multidisciplinary clinical and scientific expertise for a controversies conference on onco-nephrology to identify key management issues in nephrology relevant to patients with malignancy. This report covers the discussed controversies in kidney disease in hematological malignancies, as well as cancer after kidney transplantation. An overview of future research priorities is also discussed.
AB - The bidirectional relationship between cancer and chronic kidney disease (CKD) is complex. Patients with cancer, particularly those with hematological malignancies such as multiple myeloma and lymphoma, are at increased risk of developing acute kidney injury and CKD. On the other hand, emerging evidence from large observational registry analyses have consistently shown that cancer risk is increased by at least 2- to 3-fold in kidney transplant recipients, and the observed increased risk occurs not only in those who have received kidney transplants but also in those on dialysis and with mild- to moderate-stage CKD. The interactions between cancer and CKD have raised major therapeutic and clinical challenges in the management of these patients. Given the magnitude of the problem and uncertainties, and current controversies within the existing evidence, Kidney Disease: Improving Global Outcomes (KDIGO) assembled a global panel of multidisciplinary clinical and scientific expertise for a controversies conference on onco-nephrology to identify key management issues in nephrology relevant to patients with malignancy. This report covers the discussed controversies in kidney disease in hematological malignancies, as well as cancer after kidney transplantation. An overview of future research priorities is also discussed.
KW - chemotherapy
KW - chronic kidney disease
KW - kidney transplantation
KW - oncology
KW - tumor lysis syndrome
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U2 - 10.1016/j.kint.2020.07.012
DO - 10.1016/j.kint.2020.07.012
M3 - Article
C2 - 33276867
AN - SCOPUS:85097311110
SN - 0085-2538
VL - 98
SP - 1407
EP - 1418
JO - Kidney international
JF - Kidney international
IS - 6
ER -