Juvenile dermatomyositis

Ann M. Reed, Clarissa A. Pilkington, Brian M. Feldman, Lauren M. Pachman, Lisa G. Rider

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Children with inflammatory myopathies have clinical and laboratory features, as well as risk factors and outcomes that overlap with their adult counterparts. However, a number of important differences exist between pediatric and adult disease. Juvenile dermatomyositis (JDM), the most common of this group of illnesses in children, has an incidence of approximately 3.2 cases/million children/year. JDM has a gender ratio of 2 girls:1 boy. JDM has a mean age of 6.7 years at disease onset. The duration of active disease before the time of diagnosis alters the patients' features at presentation as well as their clinical outcomes. Environmental and genetic factors affect the child's susceptibility to these conditions and also alter the inflammatory response, adding heterogeneity to disease pathophysiology.

Original languageEnglish (US)
Title of host publicationA Clinician's Pearls and Myths in Rheumatology
PublisherSpringer London
Pages201-209
Number of pages9
ISBN (Print)9781848009332
DOIs
StatePublished - Dec 1 2009

ASJC Scopus subject areas

  • Medicine(all)

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    Reed, A. M., Pilkington, C. A., Feldman, B. M., Pachman, L. M., & Rider, L. G. (2009). Juvenile dermatomyositis. In A Clinician's Pearls and Myths in Rheumatology (pp. 201-209). Springer London. https://doi.org/10.1007/978-1-84800-934-9_19