IVUS detection of vasa vasorum blood flow distribution in coronary artery vessel wall

Regina Moritz, Diane R. Eaker, Jill L. Anderson, Timothy L. Kline, Steven M. Jorgensen, Amir Lerman, Erik L. Ritman

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

There is an increased body of evidence to suggest that the vasa vasorum play a major role in the progression and complications of vulnerable plaque leading to acute coronary syndrome. We propose that detecting changes in the flow in the vascular wall by intravascular ultrasound signals can quantify the presence of vasa vasorum. The results obtained in a porcine model of atherosclerosis suggest that intravascular ultrasound-based estimates of blood flow in the arterial wall can be used in vivo in a clinical research setting to establish the density of vasa vasorum as an indicator of plaque vulnerability.

Original languageEnglish (US)
Pages (from-to)935-940
Number of pages6
JournalJACC: Cardiovascular Imaging
Volume5
Issue number9
DOIs
StatePublished - Sep 2012

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Keywords

  • arterial wall
  • atherosclerosis
  • diffusion
  • embolization
  • perfusion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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