Original language | English (US) |
---|---|
Article number | e418 |
Journal | Neurology: Neuroimmunology and NeuroInflammation |
Volume | 5 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2018 |
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
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In: Neurology: Neuroimmunology and NeuroInflammation, Vol. 5, No. 1, e418, 01.01.2018.
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - ITPR1 autoimmunity
T2 - Frequency, neurologic phenotype, and cancer association
AU - Alfugham, Nora
AU - Gadoth, Avi
AU - Lennon, Vanda A.
AU - Komorowski, Lars
AU - Scharf, Madeleine
AU - Hinson, Shannon
AU - McKeon, Andrew
AU - Pittock, Sean J.
N1 - Funding Information: From the Department of Laboratory Medicine and Pathology (N.A., A.G., V.A.L., S.H., A.M., S.J.P.), Department of Neurology (V.A. L., A.M., S.J.P.), and Department of Immunology (V.A.L.), Mayo Clinic, Rochester, MN; and Institute for Experimental Immunology (L.K., M.S.), Affiliated to Euroimmun AG, Luebeck, Germany. Author contributions: N.A.: data collection, analysis and interpretation, and drafting of the manuscript. L.K. and M.S.: supplied critical reagents and critical revision of the manuscript. S.H., A.G., V.A.L., and A.M.: data collection and analysis and critical revision of the manuscript. S.J.P.: study concept and design, data collection, analysis, and interpretation, critical revision of the manuscript, and study supervision. Acknowledgment: The authors thank John Schmeling for technical support and Mary Curtis for secretarial assistance. Study funding: Department of Laboratory Medicine and Pathology, Mayo Clinic. Disclosure: N. Alfugham and A. Gadoth report no disclosures. V.A. Lennon holds a patent for and receives royalties from RSR/Kronus for sale of aquaporin-4 autoantibody testing kits and for commercial aquaporin-4 autoantibody testing performed outside Mayo Clinic; received research support from the NIH; has a patent pending for GFAP and MAP1B as markers of neurological autoimmunity and paraneoplastic disorders; has a potential financial interest in the technology “Aquaporin-4 as an aid for cancer diagnosis”; and receives license fee payments for Non-Mayo sites performing “home brew” diagnostic testing for aquaporin-4 autoantibody. L. Komorowski is employed by Euroimmun AG, a company that develops, produces, and manufactures immunoassays for the detection of disease-associated antibodies. M. Scharf is an employee of the Euroimmun AG, a company that develops, produces, and manufactures immunoassays for the detection of disease-associated antibodies and holds a patent for diagnostic test for the detection of autoantibodies against ITPR1. S. Hinson reports no disclosures. A. McKeon has a patent pending for GFAP and MAP1B as markers of neurological autoimmunity and paraneoplastic disorders; consulted for Grifols, MedI-mmune, and Euroimmun; and received research support from MedImmune and Euroimmun but has not received personal compensation. S.J. Pittock holds patents that relate to functional AQP4/ NMO-IgG assays and NMO-IgG as a cancer marker; has a patent Funding Information: pending for GFAP and MAP1B as markers of neurological autoimmunity and paraneoplastic disorders; consulted for Alexion, Grifols, Euroimmun, and MedImmune; and received research support from Euroimmun, Grifols, MedImmune, and Alexion, RO1 NS065829-01. All compensation for consulting activities is paid directly to Mayo Clinic. Go to Neurology.org/nn for full disclosure forms. The Article Processing Charge was funded by Department of Laboratory Medicine and Pathology, Mayo Clinic. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
PY - 2018/1/1
Y1 - 2018/1/1
UR - http://www.scopus.com/inward/record.url?scp=85044298182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044298182&partnerID=8YFLogxK
U2 - 10.1212/NXI.0000000000000418
DO - 10.1212/NXI.0000000000000418
M3 - Article
AN - SCOPUS:85044298182
SN - 2332-7812
VL - 5
JO - Neurology: Neuroimmunology and NeuroInflammation
JF - Neurology: Neuroimmunology and NeuroInflammation
IS - 1
M1 - e418
ER -