ITagPlot: An accurate computation and interactive drawing tool for tag density plot

Sung Hwan Kim; Onyeka Ezenwoye; Hwan Gue Cho; Keith D. Robertson; Jeong Hyeon Choi

doi:10.1093/bioinformatics/btv166

ITagPlot: An accurate computation and interactive drawing tool for tag density plot

Sung Hwan Kim, Onyeka Ezenwoye, Hwan Gue Cho, Keith D. Robertson, Jeong Hyeon Choi

Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

Motivation: Tag density plots are very important to intuitively reveal biological phenomena from capture-based sequencing data by visualizing the normalized read depth in a region. Results: We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summary statistics and unsupervised clustering.

Original language	English (US)
Pages (from-to)	2384-2387
Number of pages	4
Journal	Bioinformatics
Volume	31
Issue number	14
DOIs	https://doi.org/10.1093/bioinformatics/btv166
State	Published - Jul 15 2015

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/btv166

Cite this

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abstract = "Motivation: Tag density plots are very important to intuitively reveal biological phenomena from capture-based sequencing data by visualizing the normalized read depth in a region. Results: We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summary statistics and unsupervised clustering.",

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AU - Cho, Hwan Gue

AU - Robertson, Keith D.

AU - Choi, Jeong Hyeon

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ITagPlot: An accurate computation and interactive drawing tool for tag density plot

Abstract

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