Abstract
In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated using low-stringency hybridization screening of a T-lymphocyte cDNA library. The deduced amino acid sequences of chicken and human CAML show areas of extensive conservation, suggesting an evolutionarily important role in signaling.
Original language | English (US) |
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Pages (from-to) | 307-309 |
Number of pages | 3 |
Journal | Gene |
Volume | 174 |
Issue number | 2 |
DOIs | |
State | Published - 1996 |
Keywords
- CAML
- Calcineurin
- Capacitative calcium influx
- Cyclosporin
- Immunophilin
- Signal transduction
- T-cell activation
ASJC Scopus subject areas
- Genetics