Ischemic Stroke Risk in Patients With Nonvalvular Atrial Fibrillation: JACC Review Topic of the Week

Mohamad Alkhouli, Paul A. Friedman

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

The last decade has witnessed remarkable advances in pharmacological and nonpharmacological strategies for stroke prevention in patients with atrial fibrillation. However, the currently available clinical stroke risk prediction models do not account for key nonclinical factors (arrhythmia burden, left atrial physiology and anatomy, chemical and electrocardiographic markers) and other competing clinical risks. Hence, their ability to identify patients who will derive the most benefit from pharmacological and mechanical risk prevention strategies remain limited. In this paper, the authors review the current and evolving ischemic stroke risk prediction schemes in patients with nonvalvular atrial fibrillation, highlight the strengths and weaknesses of the models, and discuss the unmet needs in this field.

Original languageEnglish (US)
Pages (from-to)3050-3065
Number of pages16
JournalJournal of the American College of Cardiology
Volume74
Issue number24
DOIs
StatePublished - Dec 17 2019

Keywords

  • atrial fibrillation
  • oral anticoagulation
  • risk assessment
  • stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Ischemic Stroke Risk in Patients With Nonvalvular Atrial Fibrillation: JACC Review Topic of the Week'. Together they form a unique fingerprint.

  • Cite this