Is There a Role for Desmopressin in Liver Transplantation? A Case Report

M. M. Gonzales, D. Z. Valdes, R. Helmick, Timucin Taner, G. Vasdev

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Living donor liver transplantation reduces time and mortality on the waiting list. Bleeding is a serious complication; however, "overcorrection" of coagulopathy may lead to hepatic artery thrombosis. We report a case where desmopressin (DDAVP) was used in the management of persistent postreperfusion bleeding (44 red blood cell units transfused). After 1 dose of DDAVP, bleeding improved significantly and the recipient had an unremarkable recovery. DDAVP should be considered for persisting bleeding after correcting common coagulation abnormalities where complexity of the anastomosis may preclude the use of more aggressive procoagulant drugs in liver transplantation.

Original languageEnglish (US)
Pages (from-to)2782-2785
Number of pages4
JournalTransplantation Proceedings
Volume47
Issue number9
DOIs
StatePublished - Nov 1 2015

Fingerprint

Deamino Arginine Vasopressin
Liver Transplantation
Hemorrhage
Waiting Lists
Living Donors
Hepatic Artery
Thrombosis
Erythrocytes
Mortality
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Medicine(all)

Cite this

Is There a Role for Desmopressin in Liver Transplantation? A Case Report. / Gonzales, M. M.; Valdes, D. Z.; Helmick, R.; Taner, Timucin; Vasdev, G.

In: Transplantation Proceedings, Vol. 47, No. 9, 01.11.2015, p. 2782-2785.

Research output: Contribution to journalArticle

Gonzales, M. M. ; Valdes, D. Z. ; Helmick, R. ; Taner, Timucin ; Vasdev, G. / Is There a Role for Desmopressin in Liver Transplantation? A Case Report. In: Transplantation Proceedings. 2015 ; Vol. 47, No. 9. pp. 2782-2785.
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