Is Teriparatide Beneficial to Spinal Fusion Surgery in the Older Patient?

A Narrative Review

Nathan Wanderman, Mohammed Alvi, Yagiz Yolcu, Bayard Carlson, Arjun Sebastian, Mohamad Bydon, Brett Freedman

Research output: Contribution to journalReview article

Abstract

Since FDA approval in 2002, teriparatide has gained popularity as an anabolic therapy for the treatment of osteoporosis. Animal studies have suggested a role for teriparatide in spine surgery. Several recent studies have demonstrated adjunctive use of teriparatide in osteoporotic patients undergoing spine fusions improves fusion rates, decreases time to union, and decreases osteoporosis-related complications such as proximal junctional kyphosis. On the basis of the available literature, we outline an algorithm for the use of teriparatide in spine surgery.

Original languageEnglish (US)
Pages (from-to)182-190
Number of pages9
JournalClinical Spine Surgery
Volume32
Issue number5
DOIs
StatePublished - Jun 1 2019

Fingerprint

Teriparatide
Spinal Fusion
Spine
Osteoporosis
Kyphosis
Therapeutics

Keywords

  • BMD
  • bone mineral density
  • osteoporosis
  • spine surgery
  • teriparatide

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology

Cite this

Is Teriparatide Beneficial to Spinal Fusion Surgery in the Older Patient? A Narrative Review. / Wanderman, Nathan; Alvi, Mohammed; Yolcu, Yagiz; Carlson, Bayard; Sebastian, Arjun; Bydon, Mohamad; Freedman, Brett.

In: Clinical Spine Surgery, Vol. 32, No. 5, 01.06.2019, p. 182-190.

Research output: Contribution to journalReview article

Wanderman, Nathan ; Alvi, Mohammed ; Yolcu, Yagiz ; Carlson, Bayard ; Sebastian, Arjun ; Bydon, Mohamad ; Freedman, Brett. / Is Teriparatide Beneficial to Spinal Fusion Surgery in the Older Patient? A Narrative Review. In: Clinical Spine Surgery. 2019 ; Vol. 32, No. 5. pp. 182-190.
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