Is digoxin a drug of the past? This old drug is still useful, with some caveats

Mohammad Hassan Pervaiz, Michael G. Dickinson, Mohamad Yamani

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Digoxin has been the cornerstone of the treatment of heart failure for more than 2 centuries. Now that newer therapies have been introduced that reduce the mortality rate in heart failure and recent trials have failed to prove the same for digoxin, its use has significantly decreased. But a careful review of the multiple pharmacologic actions of digoxin and closer analysis of the results of recent trials suggest that digoxin may in fact continue to be an effective treatment for heart failure.

Original languageEnglish (US)
Pages (from-to)821-834
Number of pages14
JournalCleveland Clinic journal of medicine
Volume73
Issue number9
DOIs
StatePublished - Sep 1 2006

ASJC Scopus subject areas

  • Medicine(all)

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