Irritable bowel syndrome: New and emerging treatments

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Irritable bowel syndrome is one of the most common gastrointestinal disorders in developed nations. It is characterized by abdominal pain, altered bowel habits, and bloating. Several non-pharmacological and pharmacological agents, which target the peripheral gastrointestinal system and central nervous system, are used to treat the syndrome. The individual and societal impact of investigating and managing the syndrome is substantial, and despite newer treatments, many patients have unmet needs. Intense research at many international sites has improved the understanding of pathophysiology of the syndrome, but developing treatments that are effective, safe, and that have tolerable side effects remains a challenge. This review briefly summarizes the currently available treatments for irritable bowel syndrome then focuses on newer non-pharmacological and pharmacological therapies and recent evidence for older treatments. Recent guidelines on the treatment of irritable bowel syndrome are also discussed.

Original languageEnglish (US)
Article numberh1622
JournalBMJ (Online)
Volume350
DOIs
StatePublished - Jun 18 2015

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Irritable Bowel Syndrome
Therapeutics
Pharmacology
Developed Countries
Abdominal Pain
Habits
Central Nervous System
Guidelines
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Irritable bowel syndrome : New and emerging treatments. / Halland, Magnus; Saito Loftus, Yuri Ann.

In: BMJ (Online), Vol. 350, h1622, 18.06.2015.

Research output: Contribution to journalArticle

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