Invited editorial presents an accurate summary of the results of two randomised placebo-controlled trials of vertebroplasty

Rachelle Buchbinder, Richard H. Osborne, David Kallmes

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

• Our recent editorial in the Journal presents an accurate summary of our two randomised trials of vertebroplasty, which found no benefit of vertebroplasty over placebo. • Participants in both trials are representative of patients seen in clinical practice and who would qualify for government-subsidised funding of vertebroplasty in Australia. • Clinical experience and previous published literature are likely to have overestimated the treatment benefit of vertebroplasty for many reasons. • This is why randomised placebo-controlled trials are required to determine the efficacy of treatment interventions, particularly when the condition being treated is self-limiting and the primary end point is improvement of symptoms. • Based on the best evidence currently available, the routine use of vertebroplasty outside of the research setting for painful osteoporotic vertebral fractures appears unjustified.

Original languageEnglish (US)
Pages (from-to)338-341
Number of pages4
JournalMedical Journal of Australia
Volume192
Issue number6
DOIs
StatePublished - Mar 15 2010

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Invited editorial presents an accurate summary of the results of two randomised placebo-controlled trials of vertebroplasty'. Together they form a unique fingerprint.

  • Cite this