Introduction to Neurodegeneration

The Molecular Pathology of Dementia and Movement Disorders

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Abstract

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either the clinical syndromes or the anatomical distribution of pathology. In contrast, this book takes a different approach by using a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells or in the extracellular compartments or according to a shared pathogenetic mechanism, such as trinucleotide repeats that are a feature of specific genetic disorders.

Original languageEnglish (US)
Title of host publicationNeurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition
PublisherWiley-Blackwell
Pages1-5
Number of pages5
ISBN (Print)9781405196932
DOIs
StatePublished - Sep 21 2011

Fingerprint

Molecular Pathology
Movement Disorders
Neurodegenerative Diseases
Dementia
Trinucleotide Repeats
Inborn Genetic Diseases
Textbooks
Molecular Biology
Pathology
Proteins

Keywords

  • Alzheimer's disease (AD)
  • Creutzfeld-Jakob disease (CJD)
  • Familial british dementia (FBD)
  • Huntington's disease (HD)
  • Microglia
  • Neurodegenerative diseases and neuronal loss
  • Post-translational modification of proteins
  • Shared mechanisms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dickson, D. W. (2011). Introduction to Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. In Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition (pp. 1-5). Wiley-Blackwell. https://doi.org/10.1002/9781444341256.ch1

Introduction to Neurodegeneration : The Molecular Pathology of Dementia and Movement Disorders. / Dickson, Dennis W.

Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition. Wiley-Blackwell, 2011. p. 1-5.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dickson, DW 2011, Introduction to Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. in Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition. Wiley-Blackwell, pp. 1-5. https://doi.org/10.1002/9781444341256.ch1
Dickson DW. Introduction to Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. In Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition. Wiley-Blackwell. 2011. p. 1-5 https://doi.org/10.1002/9781444341256.ch1
Dickson, Dennis W. / Introduction to Neurodegeneration : The Molecular Pathology of Dementia and Movement Disorders. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition. Wiley-Blackwell, 2011. pp. 1-5
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