Intraventricular perineurioma: Case report

Caterina Giannini, Bernd W. Scheithauer, Joel Steinberg, Theodore J. Cosgrove

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

OBJECTIVE AND IMPORTANCE: Perineurioma, a rare benign nerve sheath neoplasm occurring in either an intraneural or soft tissue form, has never been reported to arise in the central nervous system. CLINICAL PRESENTATION: We describe the clinical, radiological, and pathological features of a perineurioma arising in the choroid plexus of the third ventricle in a 65- year-old woman and causing obstructive hydrocephalus. INTERVENTION: The lesion, apparently unassociated with a nerve, was gross totally resected by frontal craniotomy using a left-sided transcallosal approach. Short-term follow-up showed no evidence of recurrence. CONCLUSION: Perineurioma of the variety found in soft tissue may occur in the central nervous system, wherein it shows the typical light microscopic, immunohistochemical (epithelial membrane antigen- and Collagen IV-positive, S-100 protein-negative), and ultrastructural (pinocytotic vesicles, discontinuous basement membrane) features.

Original languageEnglish (US)
Pages (from-to)1478-1482
Number of pages5
JournalNeurosurgery
Volume43
Issue number6
StatePublished - Dec 1998

Fingerprint

Nerve Sheath Neoplasms
Central Nervous System
Mucin-1
Third Ventricle
Choroid Plexus
S100 Proteins
Craniotomy
Hydrocephalus
Basement Membrane
Collagen
Light
Recurrence

Keywords

  • Brain
  • Choroid plexus
  • Differential diagnosis
  • Immunohistochemistry
  • Nerve sheath tumor
  • Perineurioma

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Giannini, C., Scheithauer, B. W., Steinberg, J., & Cosgrove, T. J. (1998). Intraventricular perineurioma: Case report. Neurosurgery, 43(6), 1478-1482.

Intraventricular perineurioma : Case report. / Giannini, Caterina; Scheithauer, Bernd W.; Steinberg, Joel; Cosgrove, Theodore J.

In: Neurosurgery, Vol. 43, No. 6, 12.1998, p. 1478-1482.

Research output: Contribution to journalArticle

Giannini, C, Scheithauer, BW, Steinberg, J & Cosgrove, TJ 1998, 'Intraventricular perineurioma: Case report', Neurosurgery, vol. 43, no. 6, pp. 1478-1482.
Giannini C, Scheithauer BW, Steinberg J, Cosgrove TJ. Intraventricular perineurioma: Case report. Neurosurgery. 1998 Dec;43(6):1478-1482.
Giannini, Caterina ; Scheithauer, Bernd W. ; Steinberg, Joel ; Cosgrove, Theodore J. / Intraventricular perineurioma : Case report. In: Neurosurgery. 1998 ; Vol. 43, No. 6. pp. 1478-1482.
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