Intraventricular perineurioma: Case report

Caterina Giannini, Bernd W. Scheithauer, Joel Steinberg, Theodore J. Cosgrove

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

OBJECTIVE AND IMPORTANCE: Perineurioma, a rare benign nerve sheath neoplasm occurring in either an intraneural or soft tissue form, has never been reported to arise in the central nervous system. CLINICAL PRESENTATION: We describe the clinical, radiological, and pathological features of a perineurioma arising in the choroid plexus of the third ventricle in a 65- year-old woman and causing obstructive hydrocephalus. INTERVENTION: The lesion, apparently unassociated with a nerve, was gross totally resected by frontal craniotomy using a left-sided transcallosal approach. Short-term follow-up showed no evidence of recurrence. CONCLUSION: Perineurioma of the variety found in soft tissue may occur in the central nervous system, wherein it shows the typical light microscopic, immunohistochemical (epithelial membrane antigen- and Collagen IV-positive, S-100 protein-negative), and ultrastructural (pinocytotic vesicles, discontinuous basement membrane) features.

Original languageEnglish (US)
Pages (from-to)1478-1482
Number of pages5
JournalNeurosurgery
Volume43
Issue number6
DOIs
StatePublished - Dec 1998

Keywords

  • Brain
  • Choroid plexus
  • Differential diagnosis
  • Immunohistochemistry
  • Nerve sheath tumor
  • Perineurioma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Giannini, C., Scheithauer, B. W., Steinberg, J., & Cosgrove, T. J. (1998). Intraventricular perineurioma: Case report. Neurosurgery, 43(6), 1478-1482. https://doi.org/10.1097/00006123-199812000-00136