TY - JOUR
T1 - Intraventricular perineurioma
T2 - Case report
AU - Giannini, Caterina
AU - Scheithauer, Bernd W.
AU - Steinberg, Joel
AU - Cosgrove, Theodore J.
PY - 1998/12
Y1 - 1998/12
N2 - OBJECTIVE AND IMPORTANCE: Perineurioma, a rare benign nerve sheath neoplasm occurring in either an intraneural or soft tissue form, has never been reported to arise in the central nervous system. CLINICAL PRESENTATION: We describe the clinical, radiological, and pathological features of a perineurioma arising in the choroid plexus of the third ventricle in a 65- year-old woman and causing obstructive hydrocephalus. INTERVENTION: The lesion, apparently unassociated with a nerve, was gross totally resected by frontal craniotomy using a left-sided transcallosal approach. Short-term follow-up showed no evidence of recurrence. CONCLUSION: Perineurioma of the variety found in soft tissue may occur in the central nervous system, wherein it shows the typical light microscopic, immunohistochemical (epithelial membrane antigen- and Collagen IV-positive, S-100 protein-negative), and ultrastructural (pinocytotic vesicles, discontinuous basement membrane) features.
AB - OBJECTIVE AND IMPORTANCE: Perineurioma, a rare benign nerve sheath neoplasm occurring in either an intraneural or soft tissue form, has never been reported to arise in the central nervous system. CLINICAL PRESENTATION: We describe the clinical, radiological, and pathological features of a perineurioma arising in the choroid plexus of the third ventricle in a 65- year-old woman and causing obstructive hydrocephalus. INTERVENTION: The lesion, apparently unassociated with a nerve, was gross totally resected by frontal craniotomy using a left-sided transcallosal approach. Short-term follow-up showed no evidence of recurrence. CONCLUSION: Perineurioma of the variety found in soft tissue may occur in the central nervous system, wherein it shows the typical light microscopic, immunohistochemical (epithelial membrane antigen- and Collagen IV-positive, S-100 protein-negative), and ultrastructural (pinocytotic vesicles, discontinuous basement membrane) features.
KW - Brain
KW - Choroid plexus
KW - Differential diagnosis
KW - Immunohistochemistry
KW - Nerve sheath tumor
KW - Perineurioma
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U2 - 10.1097/00006123-199812000-00136
DO - 10.1097/00006123-199812000-00136
M3 - Article
C2 - 9848865
AN - SCOPUS:0031729942
SN - 0148-396X
VL - 43
SP - 1478
EP - 1482
JO - Neurosurgery
JF - Neurosurgery
IS - 6
ER -