Intravascular lymphomatosis presenting in the lung

S. A. Yousem, T. V. Colby

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

We report four patients who had intravascular lymphomatosis (IVL) that presented as interstitial lung disease. All four patients had progressive shortness of breath, weight loss, fever, and diffuse interstitial infiltrates on chest radiographs. Open lung biopsy samples showed an interstitial pneumonia excent for the intravascular proliferation of large lymphoid cells associated with irregular congestion, fibrin microthrombi, and intimal proliferation in vessels. This appearance corresponded to an intravascular large cell lymphoma (malignant angioendotheliomatosis [MAE], angiotropic lymphoma). The differential diagnosis of IVL with other pulmonary lymphoproliferations and intravascular malignancies is reported.

Original languageEnglish (US)
Pages (from-to)349-353
Number of pages5
JournalCancer
Volume65
Issue number2
DOIs
StatePublished - 1990

Fingerprint

Interstitial Lung Diseases
Lymphoma
Tunica Intima
Lung
Fibrin
Dyspnea
Weight Loss
Differential Diagnosis
Fever
Thorax
Lymphocytes
Biopsy
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Intravascular lymphomatosis presenting in the lung. / Yousem, S. A.; Colby, T. V.

In: Cancer, Vol. 65, No. 2, 1990, p. 349-353.

Research output: Contribution to journalArticle

Yousem, S. A. ; Colby, T. V. / Intravascular lymphomatosis presenting in the lung. In: Cancer. 1990 ; Vol. 65, No. 2. pp. 349-353.
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