Intravascular cardiac lipoproteinosis: extrarenal manifestation of lipoprotein glomerulopathy

Catherine S. Morris, Melanie C. Bois, Charles H. Aust, Ryan Thomas, Sanjeev M Sethi, Joseph Maleszewski

Research output: Contribution to journalArticlepeer-review

Abstract

Intracapillary lipoprotein thrombi are a distinct histopathologic finding described in the setting of lipoprotein glomerulopathy. The disease is associated with mutations in the apolipoprotein E gene and responds well to lipid-lowering treatments. Lipoprotein glomerulopathy is thought to primarily affect the kidneys, and lipoprotein thrombi have never been described in any other organ. Herein we present the first recognized case with extrarenal manifestations in the form of intravascular cardiac lipoprotein deposition.

Original languageEnglish (US)
Pages (from-to)6-9
Number of pages4
JournalCardiovascular Pathology
Volume42
DOIs
StatePublished - Sep 1 2019

Keywords

  • Emboli
  • Genetic
  • Lipid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cardiology and Cardiovascular Medicine

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