Intraspinal endodermal cyst: Ultrastructural study of abnormal cilia

Khang L. Ho, Dhananjay A. Chitale, Mohamed E. Salama

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Abstract

Abnormal cilia were demonstrated in the lining epithelial cells of three cases of intraspinal endodermal (bronchogenic) cyst. The changes comprised a wide spectrum of ultrastructural abnormalities, including (a) cilia with abnormal axonemal microtubules, (b) swollen cilia, (c) compound cilia with or without excessive ciliary matrix, (d) naked cilia without limiting membrane, and (e) intracytoplasmic cilia and aggregates of microtubules. Of these, compound cilia and swollen cilia were most common. Cilia with dynein arm deficiency were not observed. Ciliary abnormalities found in the present study were very similar to those described in the bronchial epithelium of various diseases. The present findings suggest that the lining epithelium of intraspinal endodermal cyst shares similar ciliogenesis and susceptibility to abnormal ciliary formation as that of the bronchial epithelium.

Original languageEnglish (US)
Pages (from-to)183-189
Number of pages7
JournalMicroscopy and Microanalysis
Volume9
Issue number3
DOIs
StatePublished - Jun 1 2003

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Keywords

  • Abnormal cilia
  • Bronchial epithelium
  • Bronchogenic cyst
  • Endodermal cyst
  • Intraspinal
  • Ultrastructure

ASJC Scopus subject areas

  • Instrumentation

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