Intra-articular bone marrow concentrate injection protocol: Short-term efficacy in osteoarthritis

Steven Sampson; Jay Smith; Hunter Vincent; Danielle Aufiero; Mona Zall; Angie Botto-Van-Bemden

doi:10.2217/rme-2016-0081

Intra-articular bone marrow concentrate injection protocol: Short-term efficacy in osteoarthritis

Steven Sampson, Jay Smith, Hunter Vincent, Danielle Aufiero, Mona Zall, Angie Botto-Van-Bemden

Physical Medicine and Rehabilitation

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Aim: Evaluate intra-articular injection of bone marrow concentrate (BMC), followed by platelet-rich plasma (PRP) injection at 8 weeks follow-up in moderate/severe osteoarthritis. Design: Single center, retrospective Case Series (n = 125). Methods: Bone marrow was aspirated/concentrated using a standardized technique. Patients received a single intra-articular injection of BMC, with follow-up injection of PRP at 8 weeks. Results: Median absolute pain reduction in all joints was five points (71.4%) on visual analog scale. Median patient satisfaction was 9.0/10, while 91.7% indicated that they would repeat the procedure and 94% said that they would recommend the procedure to a friend. Conclusion: Intra-articular injection of BMC, followed by a PRP injection, can provide short-term benefits in moderate-to-severe osteoarthritis.

Original language	English (US)
Pages (from-to)	511-520
Number of pages	10
Journal	Regenerative Medicine
Volume	11
Issue number	6
DOIs	https://doi.org/10.2217/rme-2016-0081
State	Published - Sep 2016

Keywords

bone marrow concentrate
orthobiologics
osteoarthritis
platelet-rich plasma

ASJC Scopus subject areas

Biomedical Engineering
Embryology

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title = "Intra-articular bone marrow concentrate injection protocol: Short-term efficacy in osteoarthritis",

abstract = "Aim: Evaluate intra-articular injection of bone marrow concentrate (BMC), followed by platelet-rich plasma (PRP) injection at 8 weeks follow-up in moderate/severe osteoarthritis. Design: Single center, retrospective Case Series (n = 125). Methods: Bone marrow was aspirated/concentrated using a standardized technique. Patients received a single intra-articular injection of BMC, with follow-up injection of PRP at 8 weeks. Results: Median absolute pain reduction in all joints was five points (71.4%) on visual analog scale. Median patient satisfaction was 9.0/10, while 91.7% indicated that they would repeat the procedure and 94% said that they would recommend the procedure to a friend. Conclusion: Intra-articular injection of BMC, followed by a PRP injection, can provide short-term benefits in moderate-to-severe osteoarthritis.",

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AU - Zall, Mona

AU - Botto-Van-Bemden, Angie

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